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Recombinant Human GDF-7 (Carrier-Free)
  • Recombinant Human GDF-7 (Carrier-Free)

Recombinant Human GDF-7 (Carrier-Free)

Cat No. Size Price Quantity
21-9085-U002 2 µg $80.00
21-9085-U010 10 µg $195.00
21-9085-U050 50 µg $624.00
21-9085-U100 100 µg $1,040.00
Lead time: 2-3 business days

Description

GDF-7 belongs to the TGF-beta superfamily of growth and differentiation factors. It is expressed selectively by roof plate cells that are located in the developing embryonic central nervous system, and has been shown to influence the neuronal identity of cells within the central nervous system. GDF-7 has also been implicated in the formation, maintenance, and repair of certain cartilage and ligament tissues.
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GDF-7 belongs to the TGF-beta superfamily of growth and differentiation factors. It is expressed selectively by roof plate cells that are located in the developing embryonic central nervous system, and has been shown to influence the neuronal identity of cells within the central nervous system. GDF-7 has also been implicated in the formation, maintenance, and repair of certain cartilage and ligament tissues.
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Product Details

Name Recombinant Human GDF-7 (Carrier-Free)
Cat. No. 21-9085
Alternative Names Growth/Differentiation Factor-7, BMP-12
Amino Acid Sequence TALAGTRTAQ GSGGGAGRGH GRRGRSRCSR KPLHVDFKEL GWDDWIIAPL DYEAYHCEGL CDFPLRSHLE PTNHAIIQTL LNSMAPDAAP ASCCVPARLS PISILYIDAA NNVVYKQYED MVVEACGCR
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human GDF-7 is a 28.0 kDa disulfide-linked homodimer containing two 129 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E.coli
Reactivity Human
Research Areas Proliferation, TGF-Beta Superfamily, Bones, Skeletal, Cartilage
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.