Recombinant Human GASP-1 (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-7058-U005 | 5 µg | $69.00 | ||
| 21-7058-U025 | 25 µg | $175.00 | ||
| 21-7058-U100 | 100 µg | $650.00 | ||
| 21-7058-U500 | 500 µg | $2,295.00 |
Lead time: 2-3 business days
Technical Data Sheet
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Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted protein that functions as an inhibitory binding protein of some TGF-beta family members. GASP proteins are involved in modulating lysosomal sorting and targeting receptors for lysosomal degradation.
Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted protein that functions as an inhibitory binding protein of some TGF-beta family members. GASP proteins are involved in modulating lysosomal sorting and targeting receptors for lysosomal degradation.
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Product Details
| Name | Recombinant Human GASP-1 (Carrier-free) |
|---|---|
| Cat. No. | 21-7058 |
| Alternative Names | GDF-associated serum protein-1, GASP, KIAA0443, WFIKKNRP |
| Amino Acid Sequence | LPPIRYSHAG ICPNDMNPNL WVDAQSTCRR ECETDQECET YEKCCPNVCG TKSCVAARYM DVKGKKGPVG MPKEATCDHF MCLQQGSECD IWDGQPVCKC KDRCEKEPSF TCASDGLTYY NRCYMDAEAC SKGITLAVVT CRYHFTWPNT SPPPPETTMH PTTASPETPE LDMAAPALLN NPVHQSVTMG ETVSFLCDVV GRPRPEITWE KQLEDRENVV MRPNHVRGNV VV |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | Determined by its ability to inhibit human Myostatin (GDF-8) activity in MCP-11 cells. The ED50 for this effect is 0.0025-0.0040 µg/ml in the presence of ≥ 5ng/ml of human Myostatin (GDF-8). |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant human GASP-1 is a 542 amino acid protein that migrates at an apparent molecular weight of approximately 55-66 kDa by SDS-PAGE analysis under non-reducing conditions. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 95 |
| Source | CHO cells |
| Reactivity | Human |
| Research Areas | Angiogenesis/Cardiovascular; Bone, Skeletal, Cartilage; Diabetes / Weight Regulation; Proliferation; Stem Cells & Differentiation; TGF-beta Superfamily |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.