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Recombinant Human FLT3 Ligand (Carrier-free)
  • Recombinant Human FLT3 Ligand (Carrier-free)

Recombinant Human FLT3 Ligand (Carrier-free)

Cat No. Size Price Quantity
21-8513-U002 2 µg $48.00
21-8513-U010 10 µg $134.00
21-8513-U100 100 µg $725.00
21-8513-U500 500 µg $2,394.00

Description

Human FLT3 ligand acts upon hematopoietic precursors including stem cells. Human FLT3 ligand, along with other Colony Stimulating Factors such as G-CSF or GM-CSF, have critical funtions in early B cell lineage differentiation as well as expansion of monocytes and immature dendritic cells. FLT3 ligand is a class III receptor tyrosine kinase that is involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow.
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Human FLT3 ligand acts upon hematopoietic precursors including stem cells. Human FLT3 ligand, along with other Colony Stimulating Factors such as G-CSF or GM-CSF, have critical funtions in early B cell lineage differentiation as well as expansion of monocytes and immature dendritic cells. FLT3 ligand is a class III receptor tyrosine kinase that is involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow.
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Product Details

Name Recombinant Human FLT3 Ligand (Carrier-free)
Cat. No. 21-8513
Alternative Names Fms-related tyrosine kinase 3 ligand
Amino Acid Sequence TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity The ED50 was determined by the dose-dependent stimulation of the proliferation of human AML5 cells is ? 1.0 ng/ml, corresponding to a specific activity of ≥ 1x 106 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human FLT3 Ligand is a soluble 17.6 kDa protein composed of 155 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Cancer; Cell Culture; Immune System; Proliferation; Stem Cells & Differentiation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.