Recombinant Human FGF-basic (146 a.a.) (Carrier-free)
  • Recombinant Human FGF-basic (146 a.a.) (Carrier-free)

Recombinant Human FGF-basic (146 a.a.) (Carrier-free)

Cat No. Size Price Quantity
21-8986-U010 10 µg $60.00
21-8986-U050 50 µg $135.00
21-8986-U100 100 µg $218.00
21-8986-U500 500 µg $660.00
Lead time: 2-3 business days

Description

The Fibroblast Growth Factors (FGFs) are a large family of proteins that play a key role in many aspects of development and differentiation of a variety of tissues. FGF-basic is expressed in most types of tissue and plays a role in normal development and wound healing as well as neoplastic transformation. The functional activities of FGF-basic are mediated by receptor tyrosine kinases and modulated by heparin sulfate.
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The Fibroblast Growth Factors (FGFs) are a large family of proteins that play a key role in many aspects of development and differentiation of a variety of tissues. FGF-basic is expressed in most types of tissue and plays a role in normal development and wound healing as well as neoplastic transformation. The functional activities of FGF-basic are mediated by receptor tyrosine kinases and modulated by heparin sulfate.
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Product Details

Name Recombinant Human FGF-basic (146 a.a.) (Carrier-free)
Cat. No. 21-8986
Alternative Names Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin
Amino Acid Sequence PALPEDGGSG AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH IKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTD ECFFFERLES NNYNTYRSRK YTSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant human FGF-basic (146 a.a.) is a 16.4 kDa protein consisting of 146 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Angiogenesis/Cardiovascular; Cancer; Cell Culture; FGF Superfamily; Inflammation; Neurobiology; Proliferation; Stem Cells & Differentiation; Wound Healing
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.