Recombinant Human Epiregulin (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-7046-U005 | 5 µg | $69.00 | ||
| 21-7046-U025 | 25 µg | $175.00 | ||
| 21-7046-U100 | 100 µg | $560.00 | ||
| 21-7046-U500 | 500 µg | $1,610.00 |
Technical Data Sheet
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Epiregulin is a member of the epidermal growth factor family that is expressed by peripheral blood leukocytes. It stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. Epiregulin exerts its effects through binding to the epiderman growth factor receptor and other members of the ERBB family of receptors.
Epiregulin is a member of the epidermal growth factor family that is expressed by peripheral blood leukocytes. It stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. Epiregulin exerts its effects through binding to the epiderman growth factor receptor and other members of the ERBB family of receptors.
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Product Details
| Name | Recombinant Human Epiregulin (Carrier-free) |
|---|---|
| Cat. No. | 21-7046 |
| Alternative Names | EREG |
| Amino Acid Sequence | MVAQVSITKC SSDMNGYCLH GQCIYLVDMS QNYCRCEVGY TGVRCEHFFL |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | The ED50was determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells is ? 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105units/mg. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant human Epiregulin is a 5.6 kDa monomeric protein, containing 50 amino residues, which corresponds to the mature secreted Epiregulin sequence. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E. coli |
| Reactivity | Human |
| Research Areas | Cancer |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.