Recombinant Human CX3CL1 (Fractalkine) (Carrier-free)
  • Recombinant Human CX3CL1 (Fractalkine) (Carrier-free)

Recombinant Human CX3CL1 (Fractalkine) (Carrier-free)

Cat No. Size Price Quantity
21-8239-U005 5 µg $69.00
21-8239-U020 20 µg $172.00
21-8239-U100 100 µg $555.00
21-8239-U500 500 µg $1,751.00
Lead time: 2-3 business days

Description

Fractalkine, also known as CX3CL1, is expressed in numerous cell types including neurons, intestinal epithelium, and vascular endothelium. Fractalkine is a CX3C chemokine and exists as membrane protein enhancing adhesion or a soluble form following cleavage by the matalloproteinase ADAM10. As a soluble chemokine, fractalkine has strong chemoattractant activities especially for dendritic cells, microglia, monocytes, NK cells, and T cells and regulates their trafficking through lymphatic tissues.
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Fractalkine, also known as CX3CL1, is expressed in numerous cell types including neurons, intestinal epithelium, and vascular endothelium. Fractalkine is a CX3C chemokine and exists as membrane protein enhancing adhesion or a soluble form following cleavage by the matalloproteinase ADAM10. As a soluble chemokine, fractalkine has strong chemoattractant activities especially for dendritic cells, microglia, monocytes, NK cells, and T cells and regulates their trafficking through lymphatic tissues.
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Product Details

Name Recombinant Human CX3CL1 (Fractalkine) (Carrier-free)
Cat. No. 21-8239
Alternative Names Neurotactin
Amino Acid Sequence QHHGVTKCNI TCSKMTSKIP VALLIHYQQN QASCGKRAII LETRQHRLFC ADPKEQWVKD AMQHLDRQAA ALTRNG
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by its ability to chemoattract human T cells using a concentration range of ≥ 5.0-10.0 ng/ml.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human GM-CSF is a 14.6 kDa protein composed of 128 amino acids.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas AIDS/HIV; Angiogenesis/Cardiovascular; Apoptosis; Cancer; Chemotaxis; Immune System; Inflammation ; Neurobiology; Wound Healing
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.