Recombinant Human CTGFL/WISP-2 (Carrier-Free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-9072-U005 | 5 µg | $80.00 | ||
| 21-9072-U020 | 20 µg | $195.00 | ||
| 21-9072-U100 | 100 µg | $780.00 | ||
| 21-9072-U500 | 500 µg | $2,340.00 |
Technical Data Sheet
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CTGFL/WISP-2 is a 28.6 kDa protein that belongs to the CCN family of cysteine-rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. It is composed of 3 distinct domains; the IGF-Binding Protein domain (IGF-BP), the Thrombospondin type I repeat (TSP type I), and von Willebrand Factor C motif (VWFC).
CTGFL/WISP-2 is a 28.6 kDa protein that belongs to the CCN family of cysteine-rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. It is composed of 3 distinct domains; the IGF-Binding Protein domain (IGF-BP), the Thrombospondin type I repeat (TSP type I), and von Willebrand Factor C motif (VWFC).
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Product Details
| Name | Recombinant Human CTGFL/WISP-2 (Carrier-Free) |
|---|---|
| Cat. No. | 21-9072 |
| Alternative Names | Connective Tissue Growth Factor-Like protein, CCN5, CT-58 |
| Amino Acid Sequence | MQLCPTPCTC PWPPPRCPLG VPLVLDGCGC CRVCARRLGE PCDQLHVCDA SQGLVCQPGA GPGGRGALCL LAEDDSSCEV NGRLYREGET FQPHCSIRCR CEDGGFTCVP LCSEDVRLPS WDCPHPRRVE VLGKCCPEWV CGQGGGLGTQ PLPAQGPQFS GLVSSLPPGV PCPEWSTAWG PCSTTCGLGM ATRVSNQNRF CRLETQRRLC LSRPCPPSRG RSPQNSAF |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | The ED50 was determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is between ≥ ≥ ≥ 10-20 ng/ml in the presence of 15 ng/ml of human IGF-II. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Mature human CTGFL/WISP-2 is a 24.8 kDa polypeptide protein containing 227 amino acids. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 95 |
| Source | E.coli |
| Reactivity | Human |
| Research Areas | Angiogenesis/Cardiovascular, Apoptosis |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.