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Recombinant Human CCL4 (MIP-1ß) (Carrier-free)
  • Recombinant Human CCL4 (MIP-1ß) (Carrier-free)

Recombinant Human CCL4 (MIP-1ß) (Carrier-free)

Cat No. Size Price Quantity
21-7097-U002 2 µg $69.00
21-7097-U010 10 µg $175.00
21-7097-U100 100 µg $565.00
21-7097-U500 500 µg $1,795.00

Description

CCL4 (MIP-1?) is a mitogen-inducible monokine and member of the CC chemokine family. It is a secreted protein that plays a role in the acute inflammatory response and is a chemoattractant for monocytes, neutrophils, eosinophils, NK cells, and CD4+ T lymphocytes. MIP-1 beta can signal through CCR5 and, by inducing downregulation of this receptor, can block HIV-1 infection of T cells.
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CCL4 (MIP-1?) is a mitogen-inducible monokine and member of the CC chemokine family. It is a secreted protein that plays a role in the acute inflammatory response and is a chemoattractant for monocytes, neutrophils, eosinophils, NK cells, and CD4+ T lymphocytes. MIP-1 beta can signal through CCR5 and, by inducing downregulation of this receptor, can block HIV-1 infection of T cells.
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Product Details

Name Recombinant Human CCL4 (MIP-1?) (Carrier-free)
Cat. No. 21-7097
Alternative Names Macrophage Inflammatory Protein-1?, CCL4, ACT-2, Exodus-3, LAG1
Amino Acid Sequence APMGSDPPTA CCFSYTARKL PHNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Using a concentration range of ≥ 5.0-20.0 ng/ml, activity is determined by its ability to chemoattract human blood monocytes.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human MIP-1 beta consists of 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines, and has a molecular weight of 7.6 kDa.
Protein Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas AIDS/HIV, Chemotaxis, Immune System, Inflammation, Neurobiology, Wound Healing
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.