Recombinant Human CCL20 (MIP-3a) (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-8209-U005 | 5 µg | $69.00 | ||
| 21-8209-U020 | 20 µg | $172.00 | ||
| 21-8209-U100 | 100 µg | $560.00 | ||
| 21-8209-U500 | 500 µg | $1,525.00 |
Technical Data Sheet
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MIP-3 alpha or CCL20 is a CC chemokine family member with potent chemoattractant activity towards T cells and DCs especially as well as other lymphocytes, and less substantially for neutrophils. MIP-3 alpha is induced by microbes as well as other inflammatory factors including IFN gamma and TNF-α alpha, but is downregulated by IL-10. MIP-3 alpha is expressed in a wide variety of tissues including liver, fetal lung, appendix as well as lymphoid tissues and lymph nodes and is known to be produced by activated DCs.
MIP-3 alpha or CCL20 is a CC chemokine family member with potent chemoattractant activity towards T cells and DCs especially as well as other lymphocytes, and less substantially for neutrophils. MIP-3 alpha is induced by microbes as well as other inflammatory factors including IFN gamma and TNF-α alpha, but is downregulated by IL-10. MIP-3 alpha is expressed in a wide variety of tissues including liver, fetal lung, appendix as well as lymphoid tissues and lymph nodes and is known to be produced by activated DCs.
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Product Details
| Name | Recombinant Human CCL20 (MIP-3?) (Carrier-free) |
|---|---|
| Cat. No. | 21-8209 |
| Alternative Names | Macrophage Inflammatory Protein-3 alpha, LARC, Exodus-1 |
| Amino Acid Sequence | ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | Assessed by chemoattract activity with human T cells using a concentration of 10.0-50.0 ng/ml. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant Human MIP-3? is an 8.0 kDa protein containing 70 amino acid residues. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E. coli |
| Reactivity | Human |
| Research Areas | Chemotaxis; Wound Healing |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.