Customer Service: (855) 848-6626 | 8:00 a.m - 4:30 p.m. PST | Receive a Free Mask with Orders over $300

Recombinant Human CCL20 (MIP-3a) (Carrier-free)
  • Recombinant Human CCL20 (MIP-3a) (Carrier-free)

Recombinant Human CCL20 (MIP-3a) (Carrier-free)

Cat No. Size Price Quantity
21-8209-U005 5 µg $69.00
21-8209-U020 20 µg $172.00
21-8209-U100 100 µg $560.00
21-8209-U500 500 µg $1,525.00

Description

MIP-3 alpha or CCL20 is a CC chemokine family member with potent chemoattractant activity towards T cells and DCs especially as well as other lymphocytes, and less substantially for neutrophils. MIP-3 alpha is induced by microbes as well as other inflammatory factors including IFN gamma and TNF-α alpha, but is downregulated by IL-10. MIP-3 alpha is expressed in a wide variety of tissues including liver, fetal lung, appendix as well as lymphoid tissues and lymph nodes and is known to be produced by activated DCs.
View More
MIP-3 alpha or CCL20 is a CC chemokine family member with potent chemoattractant activity towards T cells and DCs especially as well as other lymphocytes, and less substantially for neutrophils. MIP-3 alpha is induced by microbes as well as other inflammatory factors including IFN gamma and TNF-α alpha, but is downregulated by IL-10. MIP-3 alpha is expressed in a wide variety of tissues including liver, fetal lung, appendix as well as lymphoid tissues and lymph nodes and is known to be produced by activated DCs.
Hide

Product Details

Name Recombinant Human CCL20 (MIP-3?) (Carrier-free)
Cat. No. 21-8209
Alternative Names Macrophage Inflammatory Protein-3 alpha, LARC, Exodus-1
Amino Acid Sequence ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Assessed by chemoattract activity with human T cells using a concentration of 10.0-50.0 ng/ml.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human MIP-3? is an 8.0 kDa protein containing 70 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Chemotaxis; Wound Healing
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.