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Recombinant Human CCL2 (MCP-1) (Carrier-free)
  • Recombinant Human CCL2 (MCP-1) (Carrier-free)

Recombinant Human CCL2 (MCP-1) (Carrier-free)

Cat No. Size Price Quantity
21-8159-U005 5 µg $63.00
21-8159-U020 20 µg $172.00
21-8159-U100 100 µg $565.00
21-8159-U500 500 µg $1,500.00

Description

Monocyte chemotactic protein-1, MCP-1, also known as Chemokine (C-C motif) ligand 2, CCL2, is a member of the CC chemokine family and is expressed in endothelial cells, smooth muscle cells and monocytes. At sites of inflammation MCP-1 is known to recruit monocytes, memory T cells and dendritic cells. MCP-1 is implicated in the pathogenesis of psoriasis, rheumatoid arthritis and atherosclerosis.
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Monocyte chemotactic protein-1, MCP-1, also known as Chemokine (C-C motif) ligand 2, CCL2, is a member of the CC chemokine family and is expressed in endothelial cells, smooth muscle cells and monocytes. At sites of inflammation MCP-1 is known to recruit monocytes, memory T cells and dendritic cells. MCP-1 is implicated in the pathogenesis of psoriasis, rheumatoid arthritis and atherosclerosis.
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Product Details

Name Recombinant Human CCL2 (MCP-1) (Carrier-free)
Cat. No. 21-8159
Alternative Names Monocyte Chemotactic Protein-1, CCL2, MCAF
Amino Acid Sequence QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKT
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human MCP-1 (CCL2) is an 8.6 kDa protein composed of 76 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Angiogenesis/Cardiovascular; Cancer; Chemotaxis; Immune System; Inflammation; Neurobiology; Wound Healing; Allergy
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.