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Recombinant Human CCL14 (HCC-1) (66 a.a.) (Carrier-free)
  • Recombinant Human CCL14 (HCC-1) (66 a.a.) (Carrier-free)

Recombinant Human CCL14 (HCC-1) (66 a.a.) (Carrier-free)

Cat No. Size Price Quantity
21-7018-U002 2 µg $59.00
21-7018-U010 10 µg $159.00
21-7018-U100 100 µg $565.00
21-7018-U500 500 µg $1,625.00

Description

CCL14 is a member of the CC family of chemokines and is found in high concentration in human plasma. Several molecular forms of CCL14 have been identified. The CCL14 propeptide is converted from a low affinity agonist to a high affinity agonist for CCR1 by proteolytic processing by serine proteases. Mature CCL14 is found in four different forms, which are distinguished by differential N-terminal truncation and contain 74, 72, 71, or 66 amino acid residues.
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CCL14 is a member of the CC family of chemokines and is found in high concentration in human plasma. Several molecular forms of CCL14 have been identified. The CCL14 propeptide is converted from a low affinity agonist to a high affinity agonist for CCR1 by proteolytic processing by serine proteases. Mature CCL14 is found in four different forms, which are distinguished by differential N-terminal truncation and contain 74, 72, 71, or 66 amino acid residues.
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Product Details

Name Recombinant Human CCL14 (HCC-1) (66 a.a.) (Carrier-free)
Cat. No. 21-7018
Alternative Names Hemofiltrate CC Chemokine-1, HCC-1/HCC-3, NCC-2
Amino Acid Sequence GPYHPSECCF TYTTYKIPRQ RIMDYYETNS QCSKPGIVFI TKRGHSVCTN PSDKWVQDYI KDMKEN
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by its ability to chemoattract human monocytes using a concentration range of ≥ 5.0-20.0 ng/ml.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant human HCC-1 (66 a.a.) is a 7.8 kDa protein consisting of 66 amino acids including the four highly conserved residues present in CC chemokines.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Bone, Skeletal, Cartilage; Chemotaxis; Wound Healing
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.