Recombinant Human BMP-5 (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-7003-U002 | 2 µg | $76.00 | ||
| 21-7003-U010 | 10 µg | $175.00 | ||
| 21-7003-U100 | 100 µg | $795.00 | ||
| 21-7003-U500 | 500 µg | $2,295.00 |
Technical Data Sheet
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Bone Morphogenetic Proteins (BMPs) belong to the TGF-beta superfamily of proteins. BMPs elicit their effects by signaling through serine/threonine kinase receptors and play key roles in the development of nearly all organs and tissues. BMP-5 is expressed in the nervous system throughout development and also plays a role in the formation of new bone tissue in response to injury.
Bone Morphogenetic Proteins (BMPs) belong to the TGF-beta superfamily of proteins. BMPs elicit their effects by signaling through serine/threonine kinase receptors and play key roles in the development of nearly all organs and tissues. BMP-5 is expressed in the nervous system throughout development and also plays a role in the formation of new bone tissue in response to injury.
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Product Details
| Name | Recombinant Human BMP-5 (Carrier-free) |
|---|---|
| Cat. No. | 21-7003 |
| Alternative Names | Bone Morphogenic Protein 5 |
| Amino Acid Sequence | AANKRKNQNR NKSSSHQDSS RMSSVGDYNT SEQKQACKKH ELYVSFRDLG WQDWIIAPEG YAAFYCDGEC SFPLNAHMNA TNHAIVQTLV HLMFPDHVPK PCCAPTKLNA ISVLYFDDSS NVILKKYRNM VVRSCGCH |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.5-1.0 µg/ml. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant human BMP-5 is a 15.6 kDa homodimeric disulfide-linked protein consisting of two identical 138 amino acid chains. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 95 |
| Source | CHO cells |
| Reactivity | Human |
| Research Areas | Bone, Skeletal, Cartilage; Neurobiology; TGF-beta Superfamily |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.