Customer Service: (855) 848-6626 | 8:00 a.m - 4:30 p.m. PST | Receive a Free Mask with Orders over $300

Recombinant Human BMP-3 (Carrier-free)
  • Recombinant Human BMP-3 (Carrier-free)

Recombinant Human BMP-3 (Carrier-free)

Cat No. Size Price Quantity
21-7172-U010 10 µg $76.00
21-7172-U050 50 µg $175.00
21-7172-U100 100 µg $280.00
21-7172-U500 500 µg $859.00

Description

Bone Morphogenetic Proteins (BMPs) belong to the TGF-beta superfamily of proteins. BMPs elicit their effects by signaling through serine/threonine kinase receptors and play key roles in the development of nearly all organs and tissues. BMP-3, also known as osteogenin, is the most abundant BMP in adult bone and is an apparent inhibitor of pro-osteogenic BMPs. BMP-3 activates the TGF-beta/activin pathway which may antagonize the BMP pathway.
View More
Bone Morphogenetic Proteins (BMPs) belong to the TGF-beta superfamily of proteins. BMPs elicit their effects by signaling through serine/threonine kinase receptors and play key roles in the development of nearly all organs and tissues. BMP-3, also known as osteogenin, is the most abundant BMP in adult bone and is an apparent inhibitor of pro-osteogenic BMPs. BMP-3 activates the TGF-beta/activin pathway which may antagonize the BMP pathway.
Hide

Product Details

Name Recombinant Human BMP-3 (Carrier-free)
Cat. No. 21-7172
Alternative Names Bone Morphogenic Protein-3, Osteogenin, BMP-3A
Amino Acid Sequence MQWIEPRNCA RRYLKVDFAD IGWSEWIISP KSFDAYYCSG ACQFPMPKSL KPSNHATIQS IVRAVGVVPG IPEPCCVPEK MSSLSILFFD ENKNVVLKVY PNMTVESCAC R
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Inhibition of BMP-2-induced alkaline phosphatase production by ATDC-5 cells is measured.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human BMP-3 is 25.2 kDa homodimeric disulfide-linked protein consisting of amino acids 361 to 472 of the precursor protein.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 95
Source E. coli
Reactivity Human
Research Areas Angiogenesis & Cardiovascular, Differentiation, Bone and Cartilage, Apoptosis, Proliferation, TGF-beta Superfamily, Stem Cells
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.