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Recombinant Human BMP-10 (Carrier-free)
  • Recombinant Human BMP-10 (Carrier-free)

Recombinant Human BMP-10 (Carrier-free)

Cat No. Size Price Quantity
21-7006-U002 2 µg $76.00
21-7006-U010 10 µg $175.00
21-7006-U100 100 µg $795.00
21-7006-U500 500 µg $2,295.00

Description

Bone Morphogenetic Proteins (BMPs) belong to the TGF-beta superfamily of proteins. BMPs elicit their effects by signaling through serine/threonine kinase receptors and play key roles in the development of nearly all organs and tissues. Biologically active BMPs are generally homodimers although it is thought that heterodimers also exist and function in vivo. BMP-10 plays a critical role in the development of embryonic heart tissue.
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Bone Morphogenetic Proteins (BMPs) belong to the TGF-beta superfamily of proteins. BMPs elicit their effects by signaling through serine/threonine kinase receptors and play key roles in the development of nearly all organs and tissues. Biologically active BMPs are generally homodimers although it is thought that heterodimers also exist and function in vivo. BMP-10 plays a critical role in the development of embryonic heart tissue.
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Product Details

Name Recombinant Human BMP-10 (Carrier-free)
Cat. No. 21-7006
Alternative Names Bone Morphogenic Protein 10
Amino Acid Sequence NAKGNYCKRT PLYIDFKEIG WDSWIIAPPG YEAYECRGVC NYPLAEHLTP TKHAIIQALV HLKNSQKASK ACCVPTKLEP ISILYLDKGV VTYKFKYEGM AVSECGCR
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 4.0-6.0 ng/ml.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant human BMP-10 is a 24.4 kDa homodimeric disulfide-linked protein consisting of two 108 amino acid subunits, which correspond to amino acid residues 317 to 424 of the full-length BMP-10 precursor.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 95
Source HEK293 cells
Reactivity Human
Research Areas Angiogenesis/Cardiovascular; Apoptosis; Bone, Skeletal, Cartilage; Proliferation; Stem Cells & Differentiation; TGF-beta Superfamily
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.