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Recombinant Human beta-NGF (Carrier-free)
  • Recombinant Human beta-NGF (Carrier-free)

Recombinant Human beta-NGF (Carrier-free)

Cat No. Size Price Quantity
21-7007-U020 20 µg $76.00
21-7007-U100 100 µg $190.00
21-7007-U250 250 µg $395.00
21-7007-U500 500 µg $649.00

Description

Beta-NGF (Nerve Growth Factor) is a neurotrophic factor that is involved in the development of sympathetic and some sensory neurons in the peripheral nervous system. Beta-NGF also plays a role in the maintenance of neurons in the adult central nervous system. In addition to these roles in the nervous system, beta-NGF is also implicated in regulation of immune system cells.
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Beta-NGF (Nerve Growth Factor) is a neurotrophic factor that is involved in the development of sympathetic and some sensory neurons in the peripheral nervous system. Beta-NGF also plays a role in the maintenance of neurons in the adult central nervous system. In addition to these roles in the nervous system, beta-NGF is also implicated in regulation of immune system cells.
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Product Details

Name Recombinant Human beta-NGF (Carrier-free)
Cat. No. 21-7007
Alternative Names NGF-beta, b-NGF, beta Nerve Growth Factor
Amino Acid Sequence SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by its ability to stimulate chick E9 DRG neurite outgrowth. The ED50 is ? 1.0 ng/ml, corresponding to a specific activity of ≥≥≤ 1 x 106 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass The functional form of human beta-NGF is a noncovalently disulfide-linked homodimer, of two 13.5 kDa polypeptide monomers (240 total amino acid residues). The three disulfide bonds are required for biological activity.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Angiogenesis/Cardiovascular; Chemotaxis; Diabetes / Weight Regulation; Inflammation; Neurobiology; Stem Cells & Differentiation; Wound Healing
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.