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Recombinant Human BCMA (Carrier-free)
  • Recombinant Human BCMA (Carrier-free)

Recombinant Human BCMA (Carrier-free)

Cat No. Size Price Quantity
21-7137-U005 5 µg $76.00
21-7137-U020 20 µg $179.00
21-7137-U100 100 µg $800.00
21-7137-U500 500 µg $2,995.00

Description

The full length B-Cell Maturation Antigen (BCMA) is a transmembrane protein consisting of 184 amino acids. It is a member of the TNF-α receptor superfamily and is preferentially expressed by mature B-cells. This protein may play a role in B- cell development and autoimmune response, and has been reported as essential for maintaining survival of plasma cells. It has been shown to bind to BAFF and APRIL, leading to NF-kappaB and MAPK8/JNK activation and stimulating IgM production.
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The full length B-Cell Maturation Antigen (BCMA) is a transmembrane protein consisting of 184 amino acids. It is a member of the TNF-α receptor superfamily and is preferentially expressed by mature B-cells. This protein may play a role in B- cell development and autoimmune response, and has been reported as essential for maintaining survival of plasma cells. It has been shown to bind to BAFF and APRIL, leading to NF-kappaB and MAPK8/JNK activation and stimulating IgM production.
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Product Details

Name Recombinant Human BCMA (Carrier-free)
Cat. No. 21-7137
Alternative Names CD269, TNFRSF17, B cell maturation antigen, tumor necrosis factor receptor superfamily member 17
Amino Acid Sequence AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity No data available at this time.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant soluble Human BCMA is a 5.3 kDa protein comprising 50 amino acids, and correlates to the TNFR homologous region of the BCMA protein.
Protein Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Apoptosis, Inflammation, Immune System, TNF-α Superfamily
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.