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Recombinant Human BAFF Receptor (Carrier-free)
  • Recombinant Human BAFF Receptor (Carrier-free)

Recombinant Human BAFF Receptor (Carrier-free)

Cat No. Size Price Quantity
21-7136-U010 10 µg $69.00
21-7136-U050 50 µg $169.00
21-7136-U100 100 µg $280.00
21-7136-U500 500 µg $859.00

Description

The B-cell activating factor (BAFF) receptor is a type III transmembrane protein belonging to the TNFR superfamily. It is expressed in spleen, lymph node and resting B-cells, with limited expression in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF/BAFFR activities are crucial to the survival and maturation of peripheral B cells. BAFF binding to BAFFR expressed on a subset of T cells has been shown to play a role in costimulating T cell activation.
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The B-cell activating factor (BAFF) receptor is a type III transmembrane protein belonging to the TNFR superfamily. It is expressed in spleen, lymph node and resting B-cells, with limited expression in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF/BAFFR activities are crucial to the survival and maturation of peripheral B cells. BAFF binding to BAFFR expressed on a subset of T cells has been shown to play a role in costimulating T cell activation.
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Product Details

Name Recombinant Human BAFF Receptor (Carrier-free)
Cat. No. 21-7136
Alternative Names BR3, CD268, TNFRSF13C, BLyS receptor 3, BAFFR, BROMIX, CVID4, prolixin
Amino Acid Sequence MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity The expected ED50 is 2.0-4.0 μg/ml, determined by its ability to block BAFF induced mouse splenocytes survival in the presence of 1.0 μg/ml of human soluble BAFF.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human BAFFR is 7.7 kDa. It consists of 76 amino acids, corresponding to the extracellular section of the full length BAFFR protein.
Protein Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 95
Source E. coli
Reactivity Human
Research Areas TNF-α Superfamily, Immune System, Proliferation, Receptors
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.