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Recombinant Human BAFF (Carrier-free)
  • Recombinant Human BAFF (Carrier-free)

Recombinant Human BAFF (Carrier-free)

Cat No. Size Price Quantity
21-8136-U005 5 µg $100.00
21-8136-U020 20 µg $225.00
21-8136-U100 100 µg $718.00
21-8136-U250 250 µg $1,750.00
21-8136-U500 500 µg $2,995.00
Lead time: 2-3 business days

Description

BAFF, a member of the TNF-α family of ligands, is expressed in T cells, dendritic cells macrophages, monocytes. Most notably BAFF is important for proliferation, maintenance and survival of B cells although it also enhances T cell function. BAFF signals through three different TNF-α receptors TACI, BCMA and BAFF-R, with the latter being unique to B cell populations. BAFF levels are elevated in autoimmune models indicating dysregulation is involved in pathogenic states.
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BAFF, a member of the TNF-α family of ligands, is expressed in T cells, dendritic cells macrophages, monocytes. Most notably BAFF is important for proliferation, maintenance and survival of B cells although it also enhances T cell function. BAFF signals through three different TNF-α receptors TACI, BCMA and BAFF-R, with the latter being unique to B cell populations. BAFF levels are elevated in autoimmune models indicating dysregulation is involved in pathogenic states.
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Product Details

Name Recombinant Human BAFF (Carrier-free)
Cat. No. 21-8136
Alternative Names
Amino Acid Sequence AVQGPEETVT QDCLQLIADS ETPTIQKGSY TFVPWLLSFK RGSALEEKEN KILVKETGYF FIYGQVLYTD KTYAMGHLIQ RKKVHVFGDE LSLVTLFRCI QNMPETLPNN SCYSAGIAKL EEGDELQLAI PRENAQISLD GDVTFFGALK LL
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by a mouse splenocyte survival assay. The expected ED50 for this effect is 0.5-2.0 µg/ml.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass This recombinant protein is 152 amino acid residues with a molecular weight of 17 kDa.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Apoptosis; Immune System; Stem Cells & Differentiation; TNF-α Superfamily
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.