Recombinant Human Artemin (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-7096-U005 | 5 µg | $76.00 | ||
| 21-7096-U020 | 20 µg | $175.00 | ||
| 21-7096-U100 | 100 µg | $585.00 | ||
| 21-7096-U500 | 500 µg | $1,795.00 |
Lead time: 2-3 business days
Technical Data Sheet
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Artemin (ARTN) is a secreted disulfide-linked homodimer that belongs to the GDNF family of ligands. It is known to be expressed by embryonic smooth muscle cells and Schwann cells. Artemin promotes sensory neuron survival and likely plays a role in the development of the peripheral nervous system. It signals through the receptor tyrosine kinase (RET)/GFR-alpha 3 receptor complex.
Artemin (ARTN) is a secreted disulfide-linked homodimer that belongs to the GDNF family of ligands. It is known to be expressed by embryonic smooth muscle cells and Schwann cells. Artemin promotes sensory neuron survival and likely plays a role in the development of the peripheral nervous system. It signals through the receptor tyrosine kinase (RET)/GFR-alpha 3 receptor complex.
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Product Details
| Name | Recombinant Human Artemin (Carrier-free) |
|---|---|
| Cat. No. | 21-7096 |
| Alternative Names | ARTN, ART, Enovin, EVN, Neublastin NBN |
| Amino Acid Sequence | AGGPGSRARA AGARGCRLRS QLVPVRALGL GHRSDELVRF RFCSGSCRRA RSPHDLSLAS LLGAGALRPP PGSRPVSQPC CRPTRYEAVS FMDVNSTWRT VDRLSATACG CLG |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | An assay designed to measure the ability to promote neurite outgrowth and survival is used to determine activity. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant human Artemin consists of ≥ 2 identical subunits that are 113 amino acids each, resulting in a 24.2 kDa disulfide-linked homodimer. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E. coli |
| Reactivity | Human |
| Research Areas | Neurobiology, TGF-beta Superfamily |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.