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Recombinant Human ANGPTL7 (Carrier-free)
  • Recombinant Human ANGPTL7 (Carrier-free)

Recombinant Human ANGPTL7 (Carrier-free)

Cat No. Size Price Quantity
21-7170-U005 5 µg $76.00
21-7170-U020 20 µg $179.00
21-7170-U100 100 µg $800.00
21-7170-U500 500 µg $2,995.00

Description

ANGPTL7 (Angiopoietin-Like Protein 7) is a secreted glycoprotein structurally related to the angiopoietin family of growth factors, but does not bind the angiopoietin-specific receptor Tie-2. Like other angiopoietin-like proteins, it contains C-terminal (fibrinogen-like) and N-terminal (coiled) domains. It is highly expressed in avascular corneal stromal layer and trabecular meshwork, and is also known as Cornea-Derived Transcript 6 (CDT6). ANGPTL7 is thought to be a negative regulator of angiogenesis and a role as a morphogen has been suggested.
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ANGPTL7 (Angiopoietin-Like Protein 7) is a secreted glycoprotein structurally related to the angiopoietin family of growth factors, but does not bind the angiopoietin-specific receptor Tie-2. Like other angiopoietin-like proteins, it contains C-terminal (fibrinogen-like) and N-terminal (coiled) domains. It is highly expressed in avascular corneal stromal layer and trabecular meshwork, and is also known as Cornea-Derived Transcript 6 (CDT6). ANGPTL7 is thought to be a negative regulator of angiogenesis and a role as a morphogen has been suggested.
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Product Details

Name Recombinant Human ANGPTL7 (Carrier-free)
Cat. No. 21-7170
Alternative Names Angiopoietin-Like Protein 7, CDT6, Cornea-Derived Transcript 6, AngX
Amino Acid Sequence QKLSKHKTPA QPQLKAANCC EEVKELKAQV ANLSSLLSEL NKKQERDWVS VVMQVMELES NSKRMESRLT DAESKYSEMN NQIDIMQLQA AQTVTQTSAD AIYDCSSLYQ KNYRISGVYK LPPDDFLGSP ELEVFCDMET SGGGWTIIQR RKSGLVSFYR DWKQYKQGFG SIRGDFWLGN EHIHRLSRQP TRLRVEMEDW EGNLRYAEYS HFVLGNELNS YRLFLGNYTG NV
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity The ability to bind recombinant integrin αalpha V, beta 3 is measured through a functional ELISA.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human ANGPTL3 is a 38.2 kDa glycosylated protein that contains a C-terminal His-tag and is comprised of 328 amino acids. It migrates at approximately 40-50 kDa by SDS-PAGE under reducing conditions.
Protein Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source Hi-5 Insect cells
Reactivity Human
Research Areas Diabetes, Angiogensis & Cardiovascular, Lipid Metabolism
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.