Recombinant Human Adiponectin (Acrp30) (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-7165-U005 | 5 µg | $76.00 | ||
| 21-7165-U025 | 25 µg | $179.00 | ||
| 21-7165-U100 | 100 µg | $665.00 | ||
| 21-7165-U500 | 500 µg | $2,995.00 |
Technical Data Sheet
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Adiponectin, or Acrp30, is a secreted hormone protein (adipokine) that is expressed exclusively by adipocytes and is present in circulating plasma. Low plasma levels of this protein are associated with insulin resistance and obesity. Adiponectin signals through the AdipoR1 and AdipoR2 receptors, and its interaction with various growth factors may, in part, account for a role in the regulation of cell growth and tissue remodeling. This protein had been shown to exhibit both pro- and anti-inflammatory effects.
Adiponectin, or Acrp30, is a secreted hormone protein (adipokine) that is expressed exclusively by adipocytes and is present in circulating plasma. Low plasma levels of this protein are associated with insulin resistance and obesity. Adiponectin signals through the AdipoR1 and AdipoR2 receptors, and its interaction with various growth factors may, in part, account for a role in the regulation of cell growth and tissue remodeling. This protein had been shown to exhibit both pro- and anti-inflammatory effects.
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Product Details
| Name | Recombinant Human Adiponectin (Acrp30) (Carrier-free) |
|---|---|
| Cat. No. | 21-7165 |
| Alternative Names | Adipocyte Complement-Related Protein of 30 kDa, AdipoQ, APM-1, Gelatin Binding Protein, GBP-28 |
| Amino Acid Sequence | RGHHHHHHHH ETTTQGPGVL LPLPKGACTG WMAGIPGHPG HNGAPGRDGR DGTPGEKGEK GDPGLIGPKG DIGETGVPGA EGPRGFPGIQ GRKGEPGEGA YVYRSAFSVG LETYVTIPNM PIRFTKIFYN QQNHYDGSTG KFHCNIPGLY YFAYHITVYM KDVKVSLFKK DKAMLFTYDQ YQENNVDQAS GSVLLHLEVG DQVWLQVYGE GERNGLYADN DNDSTFTGFL LY |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | The expected ED50 is 3.0-6.0 μg/ml, as determined by a cytotoxicity assay using murine M1 cells. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant Human Adiponectin, a glycosylated multimer, has a calculated molecular weight of ≥ 25.9 kDa. It contains amino acids Glu-19 to Asn-244 of the precursor protein fused to an N-termina histidine tag. Under reducing conditions, the glycosylated mono |
| Protein Content | Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 97 |
| Source | Hi-5 Insect cells |
| Reactivity | Human |
| Research Areas | Diabetes, Inflammation |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.