Purified Anti-Mouse CD49b (HMa2)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 70-0491-U100 | 100 µg | $82.00 | ||
| 70-0491-U500 | 500 µg | $231.00 |
Technical Data Sheet
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The HMa2 antibody reacts with mouse CD49b, a 150 kDa glycoprotein member of the integrin αfamily. CD49b, also known as integrin αalpha2, associates non-covalently with CD29 (integrin αbeta1) to form the VLA-2 heterodimer. VLA-2 integrin αs function as cellular receptors for collagen and laminin. CD49b is expressed by platelets, intestinal epithelial cells, NK cells, epithelial cells, and a subset of CD4+ T cells. CD49b plays an essential role in mediating the adhesion of cells to the extracellular matrix.
The HMa2 antibody reacts with mouse CD49b, a 150 kDa glycoprotein member of the integrin αfamily. CD49b, also known as integrin αalpha2, associates non-covalently with CD29 (integrin αbeta1) to form the VLA-2 heterodimer. VLA-2 integrin αs function as cellular receptors for collagen and laminin. CD49b is expressed by platelets, intestinal epithelial cells, NK cells, epithelial cells, and a subset of CD4+ T cells. CD49b plays an essential role in mediating the adhesion of cells to the extracellular matrix.
Product Details
| Name | Purified Anti-Mouse CD49b (HMa2) |
|---|---|
| Cat. No. | 70-0491 |
| Alternative Names | α2 integrin α, VLA-2 α chain, integrin α?2 chain, ITGA2, HM?2 |
| Gene ID | 16398 |
| Clone | HMa2 |
| Isotype | Armenian Hamster IgG |
| Reactivity | Mouse |
| Cross Reactivity | |
| Format | Purified |
| Application | Flow Cytometry, Functional Assays |
| Citations* |
Miyake S, Sakurai T, Okumura K, Yagita H. 1994. Eur J Immunol. Sep 24;24(9):2000-22005. Noto K, Kato K, Okumura K, Yagita H. 1995. Int Immunol. May;7(5):835-842. Arase H, Saito T, Phillips JH, Lanier LL. 2001. J Immunol. Aug 1;167(3):1141-1144. Zhang Z, Ramirez NE, Yankeelov TE, Li Z, Ford LE, Qi Y, Pozzi A, Zutter MM. 2008. Blood. 111:1980-1988. |
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.