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C57Bl/6 splenocytes were stained with 0.25 ug PerCP-Cyanine5.5 Anti-Mouse CD49d (65-0492) (solid line) or 0.5 ug PerCP-Cyanine5.5 Rat IgG2b isotype control (dashed line).
  • C57Bl/6 splenocytes were stained with 0.25 ug PerCP-Cyanine5.5 Anti-Mouse CD49d (65-0492) (solid line) or 0.5 ug PerCP-Cyanine5.5 Rat IgG2b isotype control (dashed line).

PerCP-Cyanine5.5 Anti-Mouse CD49d (R1-2)

Cat No. Size Price Quantity
65-0492-U025 25 µg $115.00
65-0492-U100  100 µg $289.00

Description

The R1-2 monoclonal antibody reacts with mouse CD49d, a 150kD glycoprotein member of the integrin αfamily. CD49d is also known as integrin αalpha4 (ITGA4). Together with integrin αbeta1 (CD29), CD49d forms the VLA-4 heterodimer that serves as a receptor for fibronectin and VCAM-1. VLA-4 is widely expressed on lymphocytes, monocytes, thymocytes, and NK cells. CD49d can dimerize with integrin αbeta7 to form a receptor that binds the mucosal vascular addressin molecule, MAdCAM-1.

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The R1-2 monoclonal antibody reacts with mouse CD49d, a 150kD glycoprotein member of the integrin αfamily. CD49d is also known as integrin αalpha4 (ITGA4). Together with integrin αbeta1 (CD29), CD49d forms the VLA-4 heterodimer that serves as a receptor for fibronectin and VCAM-1. VLA-4 is widely expressed on lymphocytes, monocytes, thymocytes, and NK cells. CD49d can dimerize with integrin αbeta7 to form a receptor that binds the mucosal vascular addressin molecule, MAdCAM-1.

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Product Details

Name PerCP-Cyanine5.5 Anti-Mouse CD49d (R1-2)
Cat. No. 65-0492
Alternative Names ?4 integrin α, VLA-4 ? chain, integrin α?4, ITGA4
Gene ID 16401
Clone R1-2
Isotype Rat IgG2b, κ
Reactivity Mouse
Cross Reactivity
Format PerCP-Cyanine5.5
Application Flow Cytometry
Citations*
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.