PerCP-Cyanine5.5 Anti-Mouse CD134 (OX40) (OX-86)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 65-1341-U025 | 25 µg | $130.00 | ||
| 65-1341-U100 | 100 µg | $325.00 |
Technical Data Sheet
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The OX-86 monoclonal antibody reacts with mouse CD134, a 50kD type 1 integral membrane glycoprotein and a member of the TNF-α receptor superfamily. CD134 is also known as OX40 and is expressed on activated CD4 and CD8 T cells. CD134 is the receptor for CD252 (OX40 ligand) and the interaction of this receptor-ligand pair is implicated in T-dependent humoral responses as well as numerous aspects of T cell expansion, survival and memory. Additionally, CD134 seems to play a significant role in the pathogenesis of some autoimmune diseases.
Recent Citations:
Lee W, Kingstad-Bakke B, Kedl RM, Kawaoka Y, Suresh M. CCR2 Regulates Vaccine-Induced Mucosal T-Cell Memory to Influenza A Virus. bioRxiv. 2021 Mar 25:2021.03.24.436901. doi: 10.1101/2021.03.24.436901. PMID: 33791695; PMCID: PMC8010722.
The OX-86 monoclonal antibody reacts with mouse CD134, a 50kD type 1 integral membrane glycoprotein and a member of the TNF-α receptor superfamily. CD134 is also known as OX40 and is expressed on activated CD4 and CD8 T cells. CD134 is the receptor for CD252 (OX40 ligand) and the interaction of this receptor-ligand pair is implicated in T-dependent humoral responses as well as numerous aspects of T cell expansion, survival and memory. Additionally, CD134 seems to play a significant role in the pathogenesis of some autoimmune diseases.
Recent Citations:
Lee W, Kingstad-Bakke B, Kedl RM, Kawaoka Y, Suresh M. CCR2 Regulates Vaccine-Induced Mucosal T-Cell Memory to Influenza A Virus. bioRxiv. 2021 Mar 25:2021.03.24.436901. doi: 10.1101/2021.03.24.436901. PMID: 33791695; PMCID: PMC8010722.
Product Details
| Name | PerCP-Cyanine5.5 Anti-Mouse CD134 (OX40) (OX-86) |
|---|---|
| Cat. No. | 65-1341 |
| Alternative Names | TNFRSF4, ACT35, OX-40 |
| Gene ID | 22163 |
| Clone | OX-86 |
| Isotype | Rat IgG1, kappa |
| Reactivity | Mouse |
| Cross Reactivity | |
| Format | PerCP-Cyanine5.5 |
| Application | Flow Cytometry |
| Citations* | al-Shamkhani A, Birkeland ML, Puklavec M, Brown MH, James W, Barclay AN. 1996. Eur J Immunol. Aug;26(8):1695-1699. Higgins LM, McDonald SA, Whittle N, Crockett N, Shields JG, MacDonald TT. 1999. J Immunol. Jan 1;162(1):486-493. Weinberg AD, Wegmann KW, Funatake C, Whitham RH. 1999. J Immunol. 162:1818-1826. |
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.