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C57Bl/6 splenocytes were stimulated for 3 days with ConA and then stained with APC Anti-Mouse CD3 (20-0031) and 0.25 ug PerCP-Cyanine5.5 Anti-Mouse CD134  (65-1341) (right panel) or 0.125 ug PerCP-Cyainie5.5 Rat IgG1 (left panel).
  • C57Bl/6 splenocytes were stimulated for 3 days with ConA and then stained with APC Anti-Mouse CD3 (20-0031) and 0.25 ug PerCP-Cyanine5.5 Anti-Mouse CD134  (65-1341) (right panel) or 0.125 ug PerCP-Cyainie5.5 Rat IgG1 (left panel).

PerCP-Cyanine5.5 Anti-Mouse CD134 (OX40) (OX-86)

Cat No. Size Price Quantity
65-1341-U025 25 µg $130.00
65-1341-U100  100 µg $325.00

Description

The OX-86 monoclonal antibody reacts with mouse CD134, a 50kD type 1 integral membrane glycoprotein and a member of the TNF-α receptor superfamily. CD134 is also known as OX40 and is expressed on activated CD4 and CD8 T cells. CD134 is the receptor for CD252 (OX40 ligand) and the interaction of this receptor-ligand pair is implicated in T-dependent humoral responses as well as numerous aspects of T cell expansion, survival and memory. Additionally, CD134 seems to play a significant role in the pathogenesis of some autoimmune diseases.

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The OX-86 monoclonal antibody reacts with mouse CD134, a 50kD type 1 integral membrane glycoprotein and a member of the TNF-α receptor superfamily. CD134 is also known as OX40 and is expressed on activated CD4 and CD8 T cells. CD134 is the receptor for CD252 (OX40 ligand) and the interaction of this receptor-ligand pair is implicated in T-dependent humoral responses as well as numerous aspects of T cell expansion, survival and memory. Additionally, CD134 seems to play a significant role in the pathogenesis of some autoimmune diseases.

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Product Details

Name PerCP-Cyanine5.5 Anti-Mouse CD134 (OX40) (OX-86)
Cat. No. 65-1341
Alternative Names TNFRSF4, ACT35, OX-40
Gene ID 22163
Clone OX-86
Isotype Rat IgG1, kappa
Reactivity Mouse
Cross Reactivity
Format PerCP-Cyanine5.5
Application Flow Cytometry
Citations* al-Shamkhani A, Birkeland ML, Puklavec M, Brown MH, James W, Barclay AN. 1996. Eur J Immunol. Aug;26(8):1695-1699. Higgins LM, McDonald SA, Whittle N, Crockett N, Shields JG, MacDonald TT. 1999. J Immunol. Jan 1;162(1):486-493. Weinberg AD, Wegmann KW, Funatake C, Whitham RH. 1999. J Immunol. 162:1818-1826.
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.