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C57Bl/6 splenocytes were stained with APC Anti-Mouse CD45R (20-0452) and 0.25 ug PE Anti-Mouse CD272 (50-5954) (right panel) or 0.25 ug PE Armenian Hamster IgG (left panel).
  • C57Bl/6 splenocytes were stained with APC Anti-Mouse CD45R (20-0452) and 0.25 ug PE Anti-Mouse CD272 (50-5954) (right panel) or 0.25 ug PE Armenian Hamster IgG (left panel).

PE Anti-Mouse CD272 (BTLA) (6A6)

Cat No. Size Price Quantity
50-5954-U025 25 µg $124.00
50-5954-U100 100 µg $270.00

Description

The 6A6 antibody reacts with mouse CD272, a type 1 transmembrane glycoprotein and member of the Ig superfamily. CD272, also known as BTLA (B and T Lymphocyte Attenuator), is expressed on peripheral lymphocytes as well as developing B and T cells, macrophages, and dendritic cells. CD272 is a receptor for CD270 (HVEM) and is structurally similar to CD152 (CTLA-4) and CD279 (PD-1) and functions as a negative regulator of B and T cell responses.

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The 6A6 antibody reacts with mouse CD272, a type 1 transmembrane glycoprotein and member of the Ig superfamily. CD272, also known as BTLA (B and T Lymphocyte Attenuator), is expressed on peripheral lymphocytes as well as developing B and T cells, macrophages, and dendritic cells. CD272 is a receptor for CD270 (HVEM) and is structurally similar to CD152 (CTLA-4) and CD279 (PD-1) and functions as a negative regulator of B and T cell responses.

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Product Details

Name PE Anti-Mouse CD272 (BTLA) (6A6)
Cat. No. 50-5954
Alternative Names BTLA, B and T lymphocyte attenuator
Gene ID 208154
Clone 6A6
Isotype Armenian Hamster IgG
Reactivity Mouse
Cross Reactivity
Format PE
Application Flow Cytometry
Citations*

Watanabe N, Gavrieli M, Sedy JR, Yang J, Fallarino F, Loftin SK, Hurchla MA, Zimmerman N, Sim J, Zang X, Murphy TL, Russell JH, Allison JP, Murphy KM. 2003. Nat Immunol. Jul;4(7):670-9.

Han P, Goularte OD, Rufner K, Wilkinson B, Kaye J. 2004. J Immunol. 2004 May 15;172(10):5931-9.

Sedy JR, Gavrieli M, Potter KG, et al. 2005. Nat Immunol. 6(1):90-98.

Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.