PE Anti-Mouse CD272 (BTLA) (6A6)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 50-5954-U025 | 25 µg | $124.00 | ||
| 50-5954-U100 | 100 µg | $270.00 |
Technical Data Sheet
View All Formats
Request Custom/BulkDescription
The 6A6 antibody reacts with mouse CD272, a type 1 transmembrane glycoprotein and member of the Ig superfamily. CD272, also known as BTLA (B and T Lymphocyte Attenuator), is expressed on peripheral lymphocytes as well as developing B and T cells, macrophages, and dendritic cells. CD272 is a receptor for CD270 (HVEM) and is structurally similar to CD152 (CTLA-4) and CD279 (PD-1) and functions as a negative regulator of B and T cell responses.
The 6A6 antibody reacts with mouse CD272, a type 1 transmembrane glycoprotein and member of the Ig superfamily. CD272, also known as BTLA (B and T Lymphocyte Attenuator), is expressed on peripheral lymphocytes as well as developing B and T cells, macrophages, and dendritic cells. CD272 is a receptor for CD270 (HVEM) and is structurally similar to CD152 (CTLA-4) and CD279 (PD-1) and functions as a negative regulator of B and T cell responses.
Product Details
| Name | PE Anti-Mouse CD272 (BTLA) (6A6) |
|---|---|
| Cat. No. | 50-5954 |
| Alternative Names | BTLA, B and T lymphocyte attenuator |
| Gene ID | 208154 |
| Clone | 6A6 |
| Isotype | Armenian Hamster IgG |
| Reactivity | Mouse |
| Cross Reactivity | |
| Format | PE |
| Application | Flow Cytometry |
| Citations* |
Watanabe N, Gavrieli M, Sedy JR, Yang J, Fallarino F, Loftin SK, Hurchla MA, Zimmerman N, Sim J, Zang X, Murphy TL, Russell JH, Allison JP, Murphy KM. 2003. Nat Immunol. Jul;4(7):670-9. Han P, Goularte OD, Rufner K, Wilkinson B, Kaye J. 2004. J Immunol. 2004 May 15;172(10):5931-9. Sedy JR, Gavrieli M, Potter KG, et al. 2005. Nat Immunol. 6(1):90-98. |
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.