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C57Bl/6 splenocytes stimulated for 3 days with ConA and then stained with APC Anti-Mouse CD3 (20-0031) and 0.5 ug PE Anti-Mouse CD223 (LAG-3) (50-2231) (right panel) or 0.5 ug PE Rat IgG1 isotype control (left panel).
  • C57Bl/6 splenocytes stimulated for 3 days with ConA and then stained with APC Anti-Mouse CD3 (20-0031) and 0.5 ug PE Anti-Mouse CD223 (LAG-3) (50-2231) (right panel) or 0.5 ug PE Rat IgG1 isotype control (left panel).

PE Anti-Mouse CD223 (LAG-3) (C9B7W)

Cat No. Size Price Quantity
50-2231-U025 25 µg $65.00
50-2231-U100  100 µg $145.00

Description

The C9B7W monoclonal antibody reacts with mouse CD223, also known as Lymphocyte-activation gene 3 (LAG3). CD223 is a 70 kDa member of the Ig superfamily and is structurally homologous to CD4. Like CD4, CD223 binds to MHC Class II but with higher affinity than CD4. CD223 is expressed on T cells activated through the T cell receptor and on activated NK cells.

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The C9B7W monoclonal antibody reacts with mouse CD223, also known as Lymphocyte-activation gene 3 (LAG3). CD223 is a 70 kDa member of the Ig superfamily and is structurally homologous to CD4. Like CD4, CD223 binds to MHC Class II but with higher affinity than CD4. CD223 is expressed on T cells activated through the T cell receptor and on activated NK cells.

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Product Details

td class="data">Baixeras E, Huard B, Miossec C, et al. 1992. J Exp Med. 176(2):327-337. Hannier S, Tournier M, Bismuth G, Triebel F. 1998. J Immunol. 161(8):4058-4065. Hannier S, Triebel F. 1999. Int Immunol. 11(11):1745-1752.Huang CT, Workman CJ, Flies D, et al. 2004. Immunity. 21(4):503-513.Prigent P, El Mir S, Dréano M, Triebel F. 1999. Eur J Immunol. 29(12):3867-3876.Workman CJ, Rice DS, Dugger KJ, Kurschner C, Vignali DA. 2002. Eur J Immunol. 32(8):2255-2263.
Name PE Anti-Mouse CD223 (LAG-3) (C9B7W)
Cat. No. 50-2231
Alternative Names LAG3, LAG-3
Gene ID 16768
Clone C9B7W
Isotype Rat IgG1, kappa
Reactivity Mouse
Cross Reactivity
Format PE
Application Flow Cytometry
Citations*
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.