PE Anti-Mouse CD223 (LAG-3) (C9B7W)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 50-2231-U025 | 25 µg | $65.00 | ||
| 50-2231-U100 | 100 µg | $145.00 |
Technical Data Sheet
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The C9B7W monoclonal antibody reacts with mouse CD223, also known as Lymphocyte-activation gene 3 (LAG3). CD223 is a 70 kDa member of the Ig superfamily and is structurally homologous to CD4. Like CD4, CD223 binds to MHC Class II but with higher affinity than CD4. CD223 is expressed on T cells activated through the T cell receptor and on activated NK cells.
The C9B7W monoclonal antibody reacts with mouse CD223, also known as Lymphocyte-activation gene 3 (LAG3). CD223 is a 70 kDa member of the Ig superfamily and is structurally homologous to CD4. Like CD4, CD223 binds to MHC Class II but with higher affinity than CD4. CD223 is expressed on T cells activated through the T cell receptor and on activated NK cells.
Product Details
| Name | PE Anti-Mouse CD223 (LAG-3) (C9B7W) |
|---|---|
| Cat. No. | 50-2231 |
| Alternative Names | LAG3, LAG-3 |
| Gene ID | 16768 |
| Clone | C9B7W |
| Isotype | Rat IgG1, kappa |
| Reactivity | Mouse |
| Cross Reactivity | |
| Format | PE |
| Application | Flow Cytometry |
| Citations* | td class="data">Baixeras E, Huard B, Miossec C, et al. 1992. J Exp Med. 176(2):327-337. Hannier S, Tournier M, Bismuth G, Triebel F. 1998. J Immunol. 161(8):4058-4065. Hannier S, Triebel F. 1999. Int Immunol. 11(11):1745-1752.Huang CT, Workman CJ, Flies D, et al. 2004. Immunity. 21(4):503-513.Prigent P, El Mir S, Dréano M, Triebel F. 1999. Eur J Immunol. 29(12):3867-3876.Workman CJ, Rice DS, Dugger KJ, Kurschner C, Vignali DA. 2002. Eur J Immunol. 32(8):2255-2263.
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.