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C57Bl/6 splenocytes were stained with APC Anti-Mouse CD11b (20-0112) and 0.25 ug PE Anti-Mouse CD209b (50-2093) (right panel) or 0.25 ug PE Armenian Hamster IgG isotype control (left panel).
  • C57Bl/6 splenocytes were stained with APC Anti-Mouse CD11b (20-0112) and 0.25 ug PE Anti-Mouse CD209b (50-2093) (right panel) or 0.25 ug PE Armenian Hamster IgG isotype control (left panel).

PE Anti-Mouse CD209b (SIGN-R1) (22D1)

Cat No. Size Price Quantity
50-2093-U025 25 µg $99.00
50-2093-U100 100 µg $249.00

Description

The 22D1 monoclonal antibody reacts with mouse CD209b, also known as SIGN-R1. CD209b is a single-pass type II transmembrane C-type lectin. SIGN-R1 is expressed on marginal zone macrophages in the spleen and on lymph node medullary macrophages. Mouse CD209b is one of five homologues to human CD209 (DC-SIGN) and functions to mediate the uptake of encapsulated organisms.

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The 22D1 monoclonal antibody reacts with mouse CD209b, also known as SIGN-R1. CD209b is a single-pass type II transmembrane C-type lectin. SIGN-R1 is expressed on marginal zone macrophages in the spleen and on lymph node medullary macrophages. Mouse CD209b is one of five homologues to human CD209 (DC-SIGN) and functions to mediate the uptake of encapsulated organisms.

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Product Details

Name PE Anti-Mouse CD209b (SIGN-R1) (22D1)
Cat. No. 50-2093
Alternative Names CD209. CD209 antigen-like protein B. CDSIGN. CIRE. DC-SIGN-related protein 1. DC-SIGNR1. Dcsign. MGC130443. OtB7. SIGN-R1. SIGNR5
Gene ID
Clone 22D1
Isotype Armenian Hamster IgG
Reactivity Mouse
Cross Reactivity
Format APC
Application Flow Cytometry
Citations* Park JY, Choi HJ, Prabagar MG, Choi WS, Kim SJ, Cheong C, Park CG, Chin CY, Kang YS. 2009. Neurosci Lett. 450(3):246-251.Saunders SP, Barlow JL, Walsh CM, Bellsoi A, Smith P, McKenzie AN, Fallon PG. 2010. J Immunol. 184(5):2627-2637.Zhou Y, Kawasaki H, Hsu SC, Lee RT, Yao X, Plunkett B, Fu J, Yang K, Lee YC, Huang SK. 2010. Nat Med. 16(10):1128-33.
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.