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In Vivo Ready™ Anti-Human CD40 (G28.5)
  • In Vivo Ready™ Anti-Human CD40 (G28.5)

In Vivo Ready™ Anti-Human CD40 (G28.5)

Cat No. Size Price Quantity
40-0410-U100 100 µg $85.00
40-0410-U500 500 µg $255.00

Description

The G28.5 antibody reacts with human CD40, a 45-48 kDa glycoprotein that is a member of the TNFReceptor superfamily. CD40 is expressed on B cells, follicular dendritic cells, macrophages, endothelial cells, and fibroblasts. CD40 functions as a receptor for CD154 (CD40 ligand) and mediates a wide variety of immune and inflammatory responses including co-stimulation, B cell differentiation, isotype class switching, and germinal center formation.

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The G28.5 antibody reacts with human CD40, a 45-48 kDa glycoprotein that is a member of the TNFReceptor superfamily. CD40 is expressed on B cells, follicular dendritic cells, macrophages, endothelial cells, and fibroblasts. CD40 functions as a receptor for CD154 (CD40 ligand) and mediates a wide variety of immune and inflammatory responses including co-stimulation, B cell differentiation, isotype class switching, and germinal center formation.

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Product Details

Name In Vivo Ready™ Anti-Human CD40 (G28.5)
Cat. No. 40-0410
Alternative Names TNFRSF5
Gene ID 958
Clone G28.5
Isotype Mouse IgG1, kappa
Reactivity Human
Cross Reactivity
Format In Vivo Ready™
Application Flow Cytometry, Functional Assays
Citations*

Clark EA, Ledbetter JA. 1986. Proc Natl Acad Sci U S A. 1986; 83(12):4494-4498.

 

Zhang K, Clark EA, Saxon A. 1991. J Immunol. Mar 15;146(6):1836-42.

 

Galy AH, Spits H. 1992. J Immunol. 149(3):775-782.

 

Challa A, Pound JD, Armitage RJ, Gordon J. 1999. Allergy. Jun;54(6):576-83.

 

Cognasse F, Chavarin P, Acquart S, Sabido O, Beniguel L, Genin C, Richard Y, Garraud O. 2005. Int J Immunopathol Pharmacol. Jan-Mar;18(1):65-74.

 

Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.