FITC Anti-Mouse TER-119 (TER-119)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 35-5921-U025 | 25 µg | $20.00 | ||
| 35-5921-U100 | 100 µg | $69.00 | ||
| 35-5921-U500 | 500 µg | $117.00 |
Technical Data Sheet
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The TER-119 antibody is named for the antigen to which it binds, a 52 kDa surface protein that is associated with glycophorin-A. TER-119 is considered to be a lineage marker for later stages of erythroid cell development, as its expression begins at the pro-erythroblast stage. TER-119 antigen is not expressed at either BFU-E or CFU-E stages, i.e. prior to the pro-erythroblast stage.
Recent Publications:
Itokazu M, Onodera Y, Mori T, Inoue S, Yamagishi K, Moritake A, Iwawaki N, Shigi K, Takehara T, Higashimoto Y, Akagi M, Teramura T. Adipose-derived exosomes block muscular stem cell proliferation in aged mouse by delivering miRNA Let-7d-3p that targets transcription factor HMGA2. J Biol Chem. 2022 Jun 6:102098. doi: 10.1016/j.jbc.2022.102098. Epub ahead of print. PMID: 35679898.
Baba T, Yoshida T, Tanabe Y, et al. Cytoplasmic DNA accumulation preferentially triggers cell death of myeloid leukemia cells by interacting with intracellular DNA sensing pathway. Cell Death Dis. 2021 Mar 26;12(4):322. doi: 10.1038/s41419-021-03587-x. PMID: 33771977.
The TER-119 antibody is named for the antigen to which it binds, a 52 kDa surface protein that is associated with glycophorin-A. TER-119 is considered to be a lineage marker for later stages of erythroid cell development, as its expression begins at the pro-erythroblast stage. TER-119 antigen is not expressed at either BFU-E or CFU-E stages, i.e. prior to the pro-erythroblast stage.
Recent Publications:
Itokazu M, Onodera Y, Mori T, Inoue S, Yamagishi K, Moritake A, Iwawaki N, Shigi K, Takehara T, Higashimoto Y, Akagi M, Teramura T. Adipose-derived exosomes block muscular stem cell proliferation in aged mouse by delivering miRNA Let-7d-3p that targets transcription factor HMGA2. J Biol Chem. 2022 Jun 6:102098. doi: 10.1016/j.jbc.2022.102098. Epub ahead of print. PMID: 35679898.
Baba T, Yoshida T, Tanabe Y, et al. Cytoplasmic DNA accumulation preferentially triggers cell death of myeloid leukemia cells by interacting with intracellular DNA sensing pathway. Cell Death Dis. 2021 Mar 26;12(4):322. doi: 10.1038/s41419-021-03587-x. PMID: 33771977.
Product Details
| Name | FITC Anti-Mouse TER-119 (TER-119) |
|---|---|
| Cat. No. | 35-5921 |
| Alternative Names | TER119, Erythroid cell marker, Ly-76, Ly76 |
| Gene ID | 104231 |
| Clone | TER-119 |
| Isotype | Rat IgG2b, κ |
| Reactivity | Mouse |
| Cross Reactivity | |
| Format | FITC |
| Application | Flow Cytometry |
| Citations* |
Kiatpakdee B, Sato K, Otsuka Y, Arashiki N, Chen Y, Tsumita T, Otsu W, Yamamoto A, Kawata R, Yamazaki J, Sugimoto Y, Takada K, Mohandas N, Inaba M. Cholesterol-binding protein TSPO2 coordinates maturation and proliferation of terminally differentiating erythroblasts. J Biol Chem. 2020 May 1. pii: jbc.RA119.011679. doi: 10.1074/jbc.RA119.011679 Shiyang Li, John W. Bostick, Jian Ye, Joseph F. Urban, Jr., Dorina Avram, Liang Zhou. Aryl Hydrocarbon Receptor Signaling Cell Intrinsically Inhibits Intestinal Group 2 Innate Lymphoid Cell Function. Immunity. 2018 Nov 20;49(5):915-928.e5. doi: 10.1016/j.immuni.2018.09.015 Berent-Maoz B, Montecino-Rodriguez E, Signer RAJ, and Dorshkind K. 2012. Blood. 119: 5715-5721. (Flow cytometry) Kil LP, de Bruijn MJW, van Nimwegen M, Corneth OBJ, van Hamburg JP, Dingjan GM, Thaiss F, Rimmelzwaan GF, Elewaut D, Delsing D, van Loo PF, and Hendriks RW. 2012. Blood. 119: 3744-3756. (in vitro depletion) Hardy CL, LeMasurier JS, Belz GT, Scalzo-Inguanti K, Yao J, Xiang SD, Kanellakis P, Bobik A, Strickland DH, Rolland JM, O’Hehir RE, and Plebanski M. 2012. 188: 1431-1441. (in vitro depletion) Osada M, Inoue O, Ding G, Shirai T, Ichise H, Hirayama K, Takano K, Yatomi Y, Hirashima M, Fujii H, Suzuki-Inoue S, and Ozaki Y. 2012. J. Biol. Chem. 287: 22241-22252. (Immunofluorescence microscopy – paraffin embedded tissue) Maetens M, doumont G, De Clercq S, Francoz S, Froment P, Bellefroid E, Klingmuller U, Lozano G, and Marine J-C. 2007. Blood. 109: 2630-2633. (Immunofluorescence microscopy – OCT embedded frozen tissue) Kina T, Ikuta K, Takayama E, Wada K, Majumdar AS, Weissman IL, and Katsura Y. 2000. Br. J. Haematol. 109(2): 280-287. (Immunoprecipitation, Western blot) |
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.