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MC/9 (mouse mast cell line) cells were stained with 0.125 ug FITC Anti-Mouse Fc epsilon Receptor I alpha (35-5898) (solid line) or 0.125 ug FITC Armenian Hamster IgG isotype control (dashed line).
  • MC/9 (mouse mast cell line) cells were stained with 0.125 ug FITC Anti-Mouse Fc epsilon Receptor I alpha (35-5898) (solid line) or 0.125 ug FITC Armenian Hamster IgG isotype control (dashed line).
  • FITC Anti-Mouse Fc epsilon Receptor I alpha (FceR1) (MAR-1)

FITC Anti-Mouse Fc epsilon Receptor I alpha (FceR1) (MAR-1)

Cat No. Size Price Quantity
35-5898-U025 25 µg $34.00
35-5898-U100 100 µg $100.00

Description

The MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa), a transmembrane protein member of the Ig superfamily. This chain, together with a beta chain and two gamma chains form a tetrameric complex that supports IgE-mediated signaling and subsequent release of chemical mediators of allergy and immediate hypersensitivity. FceR1a is upregulated in the presence of IgE on those cell types which express it, such as Mast cells and Basophils.

The MAR-1 antibody is widely used both in flow cytometry and for depletion of cells in vitro / in vivo. Please choose the appropriate format for each application.

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The MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa), a transmembrane protein member of the Ig superfamily. This chain, together with a beta chain and two gamma chains form a tetrameric complex that supports IgE-mediated signaling and subsequent release of chemical mediators of allergy and immediate hypersensitivity. FceR1a is upregulated in the presence of IgE on those cell types which express it, such as Mast cells and Basophils.

The MAR-1 antibody is widely used both in flow cytometry and for depletion of cells in vitro / in vivo. Please choose the appropriate format for each application.

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Product Details

Name FITC Anti-Mouse Fc epsilon Receptor I alpha (FceR1) (MAR-1)
Cat. No. 35-5898
Alternative Names high affinity IgE receptor
Gene ID 2205
Clone MAR-1
Isotype Armenian Hamster IgG
Reactivity Mouse
Cross Reactivity
Format FITC
Application Flow Cytometry
Citations*

Shiyang Li, John W. Bostick, Jian Ye, Joseph F. Urban, Jr., Dorina Avram, Liang Zhou. Aryl Hydrocarbon Receptor Signaling Cell Intrinsically Inhibits Intestinal Group 2 Innate Lymphoid Cell Function. Immunity. 2018 Nov 20;49(5):915-928.e5. doi: 10.1016/j.immuni.2018.09.015

» View on PubMed

Mukai K, BenBarak MJ, Tachibana M, Nishida K, Karasuyama H, Taniuchi I, and Galli SJ. 2012. Blood. 120: 76-85. (Flow cytometry)

Smith KA, Harcus Y, Garbi N, Hammerling GJ, MacDonald AS, and Maizels RM. 2012. Infect. Immun. 80: 3481-3489. (in vivo depletion)

Larson D, Hubner MP, Torrero MN, Morris CP, Brankin A, Swierczewski BE, Davies SJ, Vonakis BM, and Mitre E. 2012. J. Immunol. 188: 4188-4199. (in vitro activation)

Khodoun M, Krishnamurthy D, Strait R, Kucuk Y, and Finkelman F. 2011. J. Immunol. 186: 151.4. (in vitro depletion)

Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.