Customer Service: (855) 848-6626 | 8:00 a.m - 4:30 p.m. PST | Save 35% on Ghost Dyes™

C57Bl/6 bone marrow cells were stained with APC Anti-Mouse CD45R (B220) (20-0452) and 0.25 ug biotin Anti-Mouse LPAM-1 (30-5887) (right panel) or 0.25 ug biotin Rat IgG2a isotype control (left panel) followed by Streptavidin PE.
  • C57Bl/6 bone marrow cells were stained with APC Anti-Mouse CD45R (B220) (20-0452) and 0.25 ug biotin Anti-Mouse LPAM-1 (30-5887) (right panel) or 0.25 ug biotin Rat IgG2a isotype control (left panel) followed by Streptavidin PE.

Biotin Anti-Mouse LPAM-1 (DATK32)

Cat No. Size Price Quantity
30-5887-U025 25 µg $27.00
30-5887-U100 100 µg $69.00

Description

The DATK32 antibody is specific for a combinatorial epitope of the mouse integrin αalpha 4/beta 7 (LPAM-1) heterodimer. LPAM-1 is expressed on most mature lymphocytes and sub-populations of thymocytes and bone marrow cells. It is involved in lymphocyte adhesion and migration and is a receptor for several extracellular matrix proteins including VCAM-1, fibronectin, and MAdCAM-1.

DATK32 is reported to induce LPAM-1 dependent lymphocyte aggregation and block adhesion to VCAM-1, fibronectin, and MAdCAM-1.

View More

The DATK32 antibody is specific for a combinatorial epitope of the mouse integrin αalpha 4/beta 7 (LPAM-1) heterodimer. LPAM-1 is expressed on most mature lymphocytes and sub-populations of thymocytes and bone marrow cells. It is involved in lymphocyte adhesion and migration and is a receptor for several extracellular matrix proteins including VCAM-1, fibronectin, and MAdCAM-1.

DATK32 is reported to induce LPAM-1 dependent lymphocyte aggregation and block adhesion to VCAM-1, fibronectin, and MAdCAM-1.

Hide

Product Details

Name Biotin Anti-Mouse LPAM-1 (DATK32)
Cat. No. 30-5887
Alternative Names
Gene ID
Clone DATK32
Isotype Rat IgG2a, κ
Reactivity Mouse
Cross Reactivity
Format Biotin
Application Flow Cytometry
Citations*

Andrew DP, Berlin C, Honda S, et al. 1994. J Immunol. 153(9):3847-3861.

Berlin C, Berg EL, Briskin MJ, et al. 1993. Cell. 74(1):185-195.

Bogetto L, Gabriele E, Cariati R, et al. 2000. Blood. 95:2397-2406.

Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.