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C57Bl/6 splenocytes stimulated for 3 days with ConA and then stained with PE Anti-Mouse CD8 (35-0081) and 0.5 ug APC Anti-Mouse Tim-3 (20-5870) (right panel) or 0.5 ug APC Rat IgG2a isotype control (left panel).
  • C57Bl/6 splenocytes stimulated for 3 days with ConA and then stained with PE Anti-Mouse CD8 (35-0081) and 0.5 ug APC Anti-Mouse Tim-3 (20-5870) (right panel) or 0.5 ug APC Rat IgG2a isotype control (left panel).

APC Anti-Mouse CD366 (TIM-3) (RMT3-23)

Cat No. Size Price Quantity
20-5870-U025 25 µg $85.00
20-5870-U100 100 µg $220.00

Description

The RMT3-23 antibody reacts with mouse CD366 which is also known as Tim-3 (T cell immunoglobulin and mucin domain containing protein-3). Tim-3 is expressed on activated monocytes, macrophages, dendritic cells, and mast cells. Additionally, Tim-3 is found on Th1 lymphocytes and functions as an inhibitory receptor involved in the maintenance of immune homeostasis and self tolerance.

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The RMT3-23 antibody reacts with mouse CD366 which is also known as Tim-3 (T cell immunoglobulin and mucin domain containing protein-3). Tim-3 is expressed on activated monocytes, macrophages, dendritic cells, and mast cells. Additionally, Tim-3 is found on Th1 lymphocytes and functions as an inhibitory receptor involved in the maintenance of immune homeostasis and self tolerance.

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Product Details

Name APC Anti-Mouse CD366 (TIM-3) (RMT3-23)
Cat. No. 20-5870
Alternative Names Havcr2, TIM3, Timd3
Gene ID 171285
Clone RMT3-23
Isotype Rat IgG2a, κ
Reactivity Mouse
Cross Reactivity
Format APC
Application Flow Cytometry
Citations* Oikawa T1, Kamimura Y, Akiba H, et al. 2006. J Immunol. 177(7):4281-4287.Nakae S, Iikura M, Suto H, Akiba H, Umetsu DT, Dekruyff RH, Saito H, Galli SJ.Blood. 2007. Oct 1;110(7):2565-8. Anderson AC, Joller N, Kuchroo VK. 2016. Immunity. 44(5):989-1004.
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.