APC Anti-Human CD14 (61D3)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 20-0149-T025 | 25 tests | $65.00 | ||
| 20-0149-T100 | 100 tests | $135.00 | ||
| 20-0149-T500 | 500 tests | $608.00 |
Technical Data Sheet
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The 61D3 antibody is specific for human CD14, a 53-55 kDa GPI-anchored glycoprotein. CD14 is highly expressed on monocytes and to a lesser extent on interfollicular macrophages, and some dendritic cells. Together with LPS-Binding Protein (LBP), CD14 binds to and mediates the innate immune response to bacterial lipopolysaccharide (LPS).
Recent Citations:
McMurray JL, von Borstel A, Taher TE, Syrimi E, Taylor GS, Sharif M, Rossjohn J, Remmerswaal EBM, Bemelman FJ, Vieira Braga FA, Chen X, Teichmann SA, Mohammed F, Berry AA, Lyke KE, Williamson KC, Stubbington MJT, Davey MS, Willcox CR, Willcox BE. Transcriptional profiling of human Vδ1 T cells reveals a pathogen-driven adaptive differentiation program. Cell Rep. 2022 May 24;39(8):110858. doi: 10.1016/j.celrep.2022.110858. PMID: 35613583.
The 61D3 antibody is specific for human CD14, a 53-55 kDa GPI-anchored glycoprotein. CD14 is highly expressed on monocytes and to a lesser extent on interfollicular macrophages, and some dendritic cells. Together with LPS-Binding Protein (LBP), CD14 binds to and mediates the innate immune response to bacterial lipopolysaccharide (LPS).
Recent Citations:
McMurray JL, von Borstel A, Taher TE, Syrimi E, Taylor GS, Sharif M, Rossjohn J, Remmerswaal EBM, Bemelman FJ, Vieira Braga FA, Chen X, Teichmann SA, Mohammed F, Berry AA, Lyke KE, Williamson KC, Stubbington MJT, Davey MS, Willcox CR, Willcox BE. Transcriptional profiling of human Vδ1 T cells reveals a pathogen-driven adaptive differentiation program. Cell Rep. 2022 May 24;39(8):110858. doi: 10.1016/j.celrep.2022.110858. PMID: 35613583.
Product Details
| Name | APC Anti-Human CD14 (61D3) |
|---|---|
| Cat. No. | 20-0149 |
| Alternative Names | LPS-R, Mo2 |
| Gene ID | 929 |
| Clone | 61D3 |
| Isotype | Mouse IgG1, kappa |
| Reactivity | Human |
| Cross Reactivity | |
| Format | APC |
| Application | Flow Cytometry |
| Citations* |
Burel JG, Pomaznoy M, Lindestam Arlehamn CS, et al. Circulating T cell-monocyte complexes are markers of immune perturbations. Elife. 2019;8:e46045. Published 2019 Jun 25. Hogg N, Horton MA. 1987. In: McMichael AJ, Beverley PCL, Cobbold S, et al., eds. Leucocyte Typing III: White Cell Differentiation Antigens. New York, NY: Oxford University Press; 576-602. Haziot A, Chen S, Ferrero E, Low MG, Silber R, Goyert SM. 1988. J Immunol. 141: 547-552. Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC. 1990. Science. 249: 1431-1433. |
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.