APC Annexin V
FITC Annexin V
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PE Annexin V
Yukimoto A, Watanabe T, Sunago K, Nakamura Y, Tanaka T, Koizumi Y, Yoshida O, Tokumoto Y, Hirooka M, Abe M, Hiasa Y. The long noncoding RNA of RMRP is downregulated by PERK, which induces apoptosis in hepatocellular carcinoma cells. Sci Rep. 2021 Apr 12;11(1):7926. doi: 10.1038/s41598-021-86592-6. PMID: 33846370; PMCID: PMC8041825.
7-AAD
Kodani Y, Kawata M, Suga H, Kaneko YS, Nakashima A, Kameyama T, Saito K, Nagasaki H. Characterization of Hypothalamic MCH Neuron Development in a 3D Differentiation System of Mouse Embryonic Stem Cells. eNeuro. 2022 Apr 18:ENEURO.0442-21.2022. doi: 10.1523/ENEURO.0442-21.2022. Epub ahead of print. PMID: 35437265
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Yukimoto A, Watanabe T, Sunago K, Nakamura Y, Tanaka T, Koizumi Y, Yoshida O, Tokumoto Y, Hirooka M, Abe M, Hiasa Y. The long noncoding RNA of RMRP is downregulated by PERK, which induces apoptosis in hepatocellular carcinoma cells. Sci Rep. 2021 Apr 12;11(1):7926. doi: 10.1038/s41598-021-86592-6. PMID: 33846370; PMCID: PMC8041825.
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CFSE
Meng YM, Jiang X, Zhao X, Meng Q, Wu S, Chen Y, Kong X, Qiu X, Su L, Huang C, Wang M, Liu C, Wong PP. Hexokinase 2-driven glycolysis in pericytes activates their contractility leading to tumor blood vessel abnormalities. Nat Commun. 2021 Oct 14;12(1):6011. doi: 10.1038/s41467-021-26259-y. PMID: 34650057.
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Sun Y, Lu D, Yin Y, Song J, Liu Y, Hao W, Qi F, Zhang G, Zhang X, Liu L, Lin Z, Liang H, Zhao X, Jin Y, Yin Y. PTENα functions as an immune suppressor and promotes immune resistance in PTEN-mutant cancer. Nat Commun. 2021 Aug 26;12(1):5147. doi: 10.1038/s41467-021-25417-6. PMID: 34446716.
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Ghost Dye™ Fixable Viability Dyes
Miura Y, Endo K, Komori K, Sekiya I. Clearance of senescent cells with ABT-263 improves biological functions of synovial mesenchymal stem cells from osteoarthritis patients. Stem Cell Res Ther. 2022 Jun 3;13(1):222. doi: 10.1186/s13287-022-02901-4. PMID: 35658936; PMCID: PMC9166575.
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Rivet-Noor CR, Merchak AR, Li S, Beiter RM, Lee S, Thomas JA, Fernández-Castañeda A, Shin JB, Gaultier A. Stress-induced despair behavior develops independently of the Ahr-RORγt axis in CD4 + cells. Sci Rep. 2022 May 21;12(1):8594. doi: 10.1038/s41598-022-12464-2. PMID: 35597802; PMCID: PMC9124178.
Taniguchi H, Caeser R, Chavan SS, Zhan YA, Chow A, Manoj P, Uddin F, Kitai H, Qu R, Hayatt O, Shah NS, Quintanal Villalonga Á, Allaj V, Nguyen EM, Chan J, Michel AO, Mukae H, de Stanchina E, Rudin CM, Sen T. WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC. Cell Rep. 2022 May 17;39(7):110814. doi: 10.1016/j.celrep.2022.110814. PMID: 35584676.
Avalos A, Tietsort JT, Suwankitwat N, Woods JD, Jackson SW, Christodoulou A, Morrill C, Liggitt HD, Zhu C, Li QZ, Bui KK, Park H, Iritani BM. Hem-1 regulates protective humoral immunity and limits autoantibody production in a B cell-specific manner. JCI Insight. 2022 May 9;7(9):e153597. doi: 10.1172/jci.insight.153597. PMID: 35531955; PMCID: PMC9090261.
Hiller BM, Marmion DJ, Thompson CA, Elliott NA, Federoff H, Brundin P, Mattis VB, McMahon CW, Kordower JH. Optimizing maturity and dose of iPSC-derived dopamine progenitor cell therapy for Parkinson's disease. NPJ Regen Med. 2022 Apr 21;7(1):24. doi: 10.1038/s41536-022-00221-y. PMID: 35449132; PMCID: PMC9023503.
Wu B, Zhang X, Chiang HC, Pan H, Yuan B, Mitra P, Qi L, Simonyan H, Young CN, Yvon E, Hu Y, Zhang N, Li R. RNA polymerase II pausing factor NELF in CD8+ T cells promotes antitumor immunity. Nat Commun. 2022 Apr 20;13(1):2155. doi: 10.1038/s41467-022-29869-2. PMID: 35444206; PMCID: PMC9021285.
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Brian BF 4th, Sauer ML, Greene JT, Senevirathne SE, Lindstedt AJ, Funk OL, Ruis BL, Ramirez LA, Auger JL, Swanson WL, Nunez MG, Moriarity BS, Lowell CA, Binstadt BA, Freedman TS. A dominant function of LynB kinase in preventing autoimmunity. Sci Adv. 2022 Apr 22;8(16):eabj5227. doi: 10.1126/sciadv.abj5227. Epub 2022 Apr 22. PMID: 35452291.
Gottlieb A, Toledano-Furman N, Prabhakara KS, Kumar A, Caplan HW, Bedi S, Cox CS Jr, Olson SD. Time dependent analysis of rat microglial surface markers in traumatic brain injury reveals dynamics of distinct cell subpopulations. Sci Rep. 2022 Apr 15;12(1):6289. doi: 10.1038/s41598-022-10419-1. PMID: 35428862.
Minervina AA, Pogorelyy MV, Kirk AM, Crawford JC, Allen EK, Chou CH, Mettelman RC, Allison KJ, Lin CY, Brice DC, Zhu X, Vegesana K, Wu G, Trivedi S, Kottapalli P, Darnell D, McNeely S, Olsen SR, Schultz-Cherry S, Estepp JH; SJTRC Study Team, McGargill MA, Wolf J, Thomas PG. SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8+ T cells. Nat Immunol. 2022 May;23(5):781-790. doi: 10.1038/s41590-022-01184-4. Epub 2022 Apr 5. PMID: 35383307; PMCID: PMC9106845.
Teghanemt A, Pulipati P, Misel-Wuchter K, Day K, Yorek MS, Yi R, Keen HL, Au C, Maretzky T, Gurung P, Littman DR, Issuree PD. CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element. Nat Commun. 2022 Mar 18;13(1):1477. doi: 10.1038/s41467-022-28914-4. PMID: 35304452.
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Schmit T, Guo K, Tripathi JK, Wang Z, McGregor B, Klomp M, Ambigapathy G, Mathur R, Hur J, Pichichero M, Kolls J, Khan MN. Interferon-γ promotes monocyte-mediated lung injury during influenza infection. Cell Rep. 2022 Mar 1;38(9):110456. doi: 10.1016/j.celrep.2022.110456. PMID: 35235782
Tapanes SA, Arizanovska D, Díaz MM, Folorunso OO, Harvey T, Brown SE, Radzishevsky I, Close LN, Jagid JR, Graciolli Cordeiro J, Wolosker H, Balu DT, Liebl DJ. Inhibition of glial D-serine release rescues synaptic damage after brain injury. Glia. 2022 Feb 23. doi: 10.1002/glia.24161. Epub ahead of print. PMID: 35195906.
Sánchez-Navarro A, Martínez-Rojas MÁ, Albarrán-Godinez A, Pérez-Villalva R, Auwerx J, de la Cruz A, Noriega LG, Rosetti F, Bobadilla NA. Sirtuin 7 Deficiency Reduces Inflammation and Tubular Damage Induced by an Episode of Acute Kidney Injury. Int J Mol Sci. 2022 Feb 25;23(5):2573. doi: 10.3390/ijms23052573. PMID: 35269715.
Hong H, Lee J, Park GY, Kim S, Park J, Park JS, Song Y, Lee S, Kim TJ, Lee YJ, Roh TY, Kwok SK, Kim SW, Tan Q, Lee Y. Postnatal regulation of B-1a cell development and survival by the CIC-PER2-BHLHE41 axis. Cell Rep. 2022 Feb 15;38(7):110386. doi: 10.1016/j.celrep.2022.110386. PMID: 35172136.
Levack RC, Newell KL, Cabrera-Martinez B, Cox J, Perl A, Bastacky SI, Winslow GM. Adenosine receptor 2a agonists target mouse CD11c+T-bet+ B cells in infection and autoimmunity. Nat Commun. 2022 Jan 21;13(1):452. doi: 10.1038/s41467-022-28086-1. PMID: 35064115.
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Yan C, Chen SC, Ayers GD, Nebhan CA, Roland JT, Weiss VL, Johnson DB, Richmond A. Proximity of immune and tumor cells underlies response to BRAF/MEK-targeted therapies in metastatic melanoma patients. NPJ Precis Oncol. 2022 Jan 20;6(1):6. doi: 10.1038/s41698-021-00249-1. PMID: 35058553.
Jacqueline C, Dracz M, Xue J, Binder RJ, Minden J, Finn O. LCVM infection generates tumor antigen-specific immunity and inhibits growth of nonviral tumors. Oncoimmunology. 2022 Jan 21;11(1):2029083. doi: 10.1080/2162402X.2022.2029083. PMID: 35083098; PMCID: PMC8786340.
Fahl SP, Sertori R, Zhang Y, Contreras AV, Harris B, Wang M, Perrigoue J, Balachandran S, Kennedy BK, Wiest DL. Loss of Ribosomal Protein Paralog Rpl22-like1 Blocks Lymphoid Development without Affecting Protein Synthesis. J Immunol. 2022 Jan 19:ji2100668. doi: 10.4049/jimmunol.2100668. Epub ahead of print. PMID: 35046107.
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Mergaert AM, Denny MF, Kingstad-Bakke B, Bawadekar M, Bashar SJ, Warner TF, Suresh M, Shelef MA. Peptidylarginine Deiminase 2 in Murine Antiviral and Autoimmune Antibody Responses. J Immunol Res. 2022 Jan 17;2022:5258221. doi: 10.1155/2022/5258221. PMID: 35083342; PMCID: PMC8786467.
Torphy RJ, Sun Y, Lin R, Caffrey-Carr A, Fujiwara Y, Ho F, Miller EN, McCarter MD, Lyons TR, Schulick RD, Kedl RM, Zhu Y. GPR182 limits antitumor immunity via chemokine scavenging in mouse melanoma models. Nat Commun. 2022 Jan 10;13(1):97. doi: 10.1038/s41467-021-27658-x. PMID: 35013216.
Ghosh S, Raundhal M, Myers SA, Carr SA, Chen X, Petsko GA, Glimcher LH. Identification of RIOK2 as a master regulator of human blood cell development. Nat Immunol. 2022 Jan;23(1):109-121. doi: 10.1038/s41590-021-01079-w. Epub 2021 Dec 22. PMID: 34937919.
Wu D, Poholek CH, Majumder S, Liu Q, Revu SK, Mohib K, Rothstein DM, McGeachy MJ. IL-17-dependent fibroblastic reticular cell training boosts tissue protective mucosal immunity through IL-10-producing B cells. Sci Immunol. 2021 Dec 17;6(66):eaao3669. doi: 10.1126/sciimmunol.aao3669. Epub 2021 Dec 17. PMID: 34919443.
Raihan MO, McGregor BA, Velaris NA, Brishti A, Hur J, Porter JE. Method of Microglial DNA-RNA Purification from a Single Brain of an Adult Mouse. Methods Protoc. 2021 Dec 2;4(4):86. doi: 10.3390/mps4040086. PMID: 34940397; PMCID: PMC8704779.
Honda M, Kadohisa M, Yoshii D, Komohara Y, Hibi T. Directly recruited GATA6 + peritoneal cavity macrophages contribute to the repair of intestinal serosal injury. Nat Commun. 2021 Dec 15;12(1):7294. doi: 10.1038/s41467-021-27614-9. PMID: 34911964.
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Wan Z, Sun R, Liu YW, Li S, Sun J, Li J, Zhu J, Moharil P, Zhang B, Ren P, Ren G, Zhang M, Ma X, Dai S, Yang D, Lu B, Li S. Targeting metabotropic glutamate receptor 4 for cancer immunotherapy. Sci Adv. 2021 Dec 10;7(50):eabj4226. doi: 10.1126/sciadv.abj4226. Epub 2021 Dec 10. PMID: 34890233.
Wilfahrt D, Philips RL, Lama J, Kizerwetter M, Shapiro MJ, McCue SA, Kennedy MM, Rajcula MJ, Zeng H, Shapiro VS. Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation. Elife. 2021 Dec 2;10:e70978. doi: 10.7554/eLife.70978. PMID: 34854376; PMCID: PMC8639145.
Kim EJ, Liu P, Zhang S, Donahue K, Wang Y, Schehr JL, Wolfe SK, Dickerson A, Lu L, Rui L, Zhong X, Wisinski KB, Yu M, Suzuki A, Lang JM, Ong IM, Xu W. BAF155 methylation drives metastasis by hijacking super-enhancers and subverting anti-tumor immunity. Nucleic Acids Res. 2021 Dec 2;49(21):12211-12233. doi: 10.1093/nar/gkab1122. PMID: 34865122.
Nyhoff LE, Griffith AS, Clark ES, Thomas JW, Khan WN, Kendall PL. Btk Supports Autoreactive B Cell Development and Protects against Apoptosis but Is Expendable for Antigen Presentation. J Immunol. 2021 Nov 19:ji2000558. doi: 10.4049/jimmunol.2000558. Epub ahead of print. PMID: 34799428.
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Young IC, Wu B, Andricovich J, Chuang ST, Li R, Tzatsos A, Wu RC, Wu MY. Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling. Cell Rep. 2021 Nov 23;37(8):110036. doi: 10.1016/j.celrep.2021.110036. PMID: 34818550.
Prinzing B, Zebley CC, Petersen CT, Fan Y, Anido AA, Yi Z, Nguyen P, Houke H, Bell M, Haydar D, Brown C, Boi SK, Alli S, Crawford JC, Riberdy JM, Park JJ, Zhou S, Velasquez MP, DeRenzo C, Lazzarotto CR, Tsai SQ, Vogel P, Pruett-Miller SM, Langfitt DM, Gottschalk S, Youngblood B, Krenciute G. Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity. Sci Transl Med. 2021 Nov 17;13(620):eabh0272. doi: 10.1126/scitranslmed.abh0272. Epub 2021 Nov 17. PMID: 34788079.
Stephens WZ, Kubinak JL, Ghazaryan A, Bauer KM, Bell R, Buhrke K, Chiaro TR, Weis AM, Tang WW, Monts JK, Soto R, Ekiz HA, O'Connell RM, Round JL. Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition. Cell Rep. 2021 Nov 2;37(5):109916. doi: 10.1016/j.celrep.2021.109916. PMID: 34731608.
Fiege JK, Block KE, Pierson MJ, Nanda H, Shepherd FK, Mickelson CK, Stolley JM, Matchett WE, Wijeyesinghe S, Meyerholz DK, Vezys V, Shen SS, Hamilton SE, Masopust D, Langlois RA. Mice with diverse microbial exposure histories as a model for preclinical vaccine testing. Cell Host Microbe. 2021 Oct 27:S1931-3128(21)00463-7. doi: 10.1016/j.chom.2021.10.001. Epub ahead of print. PMID: 34731647.
Sturmlechner I, Zhang C, Sine CC, van Deursen EJ, Jeganathan KB, Hamada N, Grasic J, Friedman D, Stutchman JT, Can I, Hamada M, Lim DY, Lee JH, Ordog T, Laberge RM, Shapiro V, Baker DJ, Li H, van Deursen JM. p21 produces a bioactive secretome that places stressed cells under immunosurveillance. Science. 2021 Oct 29;374(6567):eabb3420. doi: 10.1126/science.abb3420. Epub 2021 Oct 29. PMID: 34709885.
Boothby IC, Kinet MJ, Boda DP, Kwan EY, Clancy S, Cohen JN, Habrylo I, Lowe MM, Pauli M, Yates AE, Chan JD, Harris HW, Neuhaus IM, McCalmont TH, Molofsky AB, Rosenblum MD. Early-life inflammation primes a T helper 2 cell-fibroblast niche in skin. Nature. 2021 Oct 27. doi: 10.1038/s41586-021-04044-7. Epub ahead of print. PMID: 34707292.
Morgan PK, Huynh K, Pernes G, Miotto PM, Mellett NA, Giles C, Meikle PJ, Murphy AJ, Lancaster GI. Macrophage polarization state affects lipid composition and the channelling of exogenous fatty acids into endogenous lipid pools. J Biol Chem. 2021 Oct 22:101341. doi: 10.1016/j.jbc.2021.101341. PMID: 34695418.
Ayupe AC, Beckedorff F, Levay K, Yon B, Salgueiro Y, Shiekhattar R, Park KK. Identification of long noncoding RNAs in injury-resilient and injury-susceptible mouse retinal ganglion cells. BMC Genomics. 2021 Oct 14;22(1):741. doi: 10.1186/s12864-021-08050-x. PMID: 34649511.
Zebley CC, Abdelsamed HA, Ghoneim HE, Alli S, Brown C, Haydar D, Mi T, Harris T, McGargill MA, Krenciute G, Youngblood B. Proinflammatory cytokines promote TET2-mediated DNA demethylation during CD8 T cell effector differentiation. Cell Rep. 2021 Oct 12;37(2):109796. doi: 10.1016/j.celrep.2021.109796. PMID: 34644568.
Jin YB, Cao X, Shi CW, et al. Lactobacillus rhamnosus GG Promotes Early B Lineage Development and IgA Production in the Lamina Propria in Piglets. J Immunol. 2021 Sep 8: ji2100102. doi: 10.4049/jimmunol.2100102. PMID: 34497150.
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Lopez-Ichikawa M, Vu NK, Nijagal A, Rubinsky B, Chang TT. Neutrophils are important for the development of pro-reparative macrophages after irreversible electroporation of the liver in mice. Sci Rep. 2021 Jul 22;11(1):14986. doi: 10.1038/s41598-021-94016-8. PMID: 34294763.
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Xu C, Sun S, Johnson T, Qi R, Zhang S, Zhang J, Yang K. The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity. Cell Rep. 2021 Jun 15;35(11):109235. doi: 10.1016/j.celrep.2021.109235. PMID: 34133924.
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Hamilton JR, Tsuchida CA, Nguyen DN, et al. Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering. Cell Rep. 2021 Jun 1;35(9):109207. doi: 10.1016/j.celrep.2021.109207. PMID: 34077734.
Davenport BJ, Morrison TE, Kedl RM, Klarquist J. Conserved and Novel Mouse CD8 T Cell Epitopes within SARS-CoV-2 Spike Receptor Binding Domain Protein Identified following Subunit Vaccination. J Immunol. 2021 May 10:ji2100195. doi: 10.4049/jimmunol.2100195. PMID: 33972373.
Franciosa G, Smits JGA, Minuzzo S, Martinez-Val A, Indraccolo S, Olsen JV. Proteomics of resistance to Notch1 inhibition in acute lymphoblastic leukemia reveals targetable kinase signatures. Nat Commun. 2021 May 4;12(1):2507. doi: 10.1038/s41467-021-22787-9. PMID: 33947863.
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