Brefeldin A Solution
Lam LKM, Watson AM, Ryman KD, Klimstra WB. Gamma-interferon exerts a critical early restriction on replication and dissemination of yellow fever virus vaccine strain 17D-204. NPJ Vaccines. 2018;3:5. Published 2018 Jan 23. doi:10.1038/s41541-017-0039-z.
Cell Stimulation Cocktail (500X)
Dhariwala MO, Karthikeyan D, Vasquez KS, et al. Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature. Cell Rep Med. 2020 Nov 3;1(8):100132. doi: 10.1016/j.xcrm.2020.100132. PMID: 33294857; PMCID: PMC7691438.
Brincks E. L., Adams J., Wang L., Turner B., Marcinowicz A., Ke J., Essmann M., Mautino L. M., Allen C. Van, Kumar S., Vahanian N., Link C., Mautino M. R. et al Indoximod opposes the immunosuppressive effects mediated by IDO and TDO via modulation of AhR function and activation of mTORC1. Oncotarget. 2020; 11: 2438-2461.
Cordoro KM, Hitraya-Low M, Taravati K, Sandoval PM, Kim E, Sugarman J, Pauli ML, Liao W and Rosenblum MD. 2017. Skin-infiltrating, interleukin-22-producing T cells differentiate pediatric psoriasis from adult psoriasis. J Am Acad Dermatol. doi: 10.1016/j.jaad.2017.05.017.
Flow Cytometry Perm Buffer (10X), TNB-1213
Jesser EA, Brady NJ, Huggins DN, Witschen PM, O'Connor CH, Schwertfeger KL. STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment. Breast Cancer Res. 2021 Nov 7;23(1):104. doi: 10.1186/s13058-021-01481-0. PMID: 34743736; PMCID: PMC8573892.
Xu K, Li MO. Delivery of membrane impermeable molecules to primary mouse T lymphocytes. STAR Protoc. 2021 Aug 17;2(3):100757. doi: 10.1016/j.xpro.2021.100757. PMID: 34458872; PMCID: PMC8377589.
Poudel B, Yorek MS, Mazgaeen L, Brown SA, Kanneganti TD, Gurung P. Acute IL-4 Governs Pathogenic T Cell Responses during Leishmania major Infection. Immunohorizons. 2020 Sep 18;4(9):546-560. doi: 10.4049/immunohorizons.2000076. PMID: 32948646.
Kotov JA, Kotov DI, Linehan JL, Bardwell VJ, Gearhart MD, Jenkins MK. BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors. J Exp Med. 2019;216(6):1450-1464. doi:10.1084/jem.20182376.
Colombo E, Tentorio P, Musio S, Rajewsky K, Pedotti R, Casola S and Farina C. 2014. Skewed B cell differentiation affects lymphoid organogenesis but not T cell-mediated autoimmunity. Clin Exp Immunol. 176(1): 58-65.
Khan TN, Mooster JL, Kilgore AM, Osborn JF, and Nolz JC. 2016. Local Antigen in Nonlymphoid Tissue Promotes Resident Memory CD8+ T Cell Formation During Viral Infection. The Journal of Experimental Medicine. doi: 10.1084/jem.20151855
Ashley SL, Pretto CD, Stier MT, Kadiyala P, Castro-Jorge L, Hsu TH, Doherty R, Carnahan KE, Castro MG, Lowenstein PD and Spindler KR. 2017. Matrix Metalloproteinase Activity in Infections by an Encephalitic Virus, Mouse Adenovirus Type 1. J. Virol. doi: 10.1128/JVI.01412-16
Kevin C. Osum, Adam L. Burrack, Tijana Martinov, Nathanael L. Sahli, Jason S. Mitchell, Christopher G. Tucker, Kristen E. Pauken, Klearchos Papas, Balamurugan Appakalai, Justin A. Spanier, & Brian T. Fife. Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes. Sci Rep. 2018 May 29;8(1):8295. doi: 10.1038/s41598-018-26471-9
» View on PubMed
Lesteberg K, Orange J and Makedonas G. 2017. Recycling endosomes in human cytotoxic T lymphocytes constitute an auxiliary intracellular trafficking pathway for newly synthesized perforin. Immunol Res. doi: 10.1007/s12026-017-8945-8.
Foxp3 / Transcription Factor Staining Buffer Kit, TNB-0607
Poon MML, Rybkina K, Kato Y, Kubota M, Matsumoto R, Bloom NI, Zhang Z, Hastie KM, Grifoni A, Weiskopf D, Wells SB, Ural BB, Lam N, Szabo PA, Dogra P, Lee YS, Gray JI, Bradley MC, Brusko MA, Brusko TM, Saphire EO, Connors TJ, Sette A, Crotty S, Farber DL. SARS-CoV-2 infection generates tissue-localized immunological memory in humans. Sci Immunol. 2021 Oct 7:eabl9105. doi: 10.1126/sciimmunol.abl9105. PMID: 34618554.
Yoast RE, Emrich SM, Zhang X, Xin P, Arige V, Pathak T, Benson JC, Johnson MT, Abdelnaby AE, Lakomski N, Hempel N, Han JM, Dupont G, Yule DI, Sneyd J, Trebak M. The Mitochondrial Ca2+ Uniporter is a Central Regulator of Interorganellar Ca2+ Transfer and NFAT Activation. J Biol Chem. 2021 Sep 6:101174. doi: 10.1016/j.jbc.2021.101174. PMID: 34499925.
Lei Y, Guerra Martinez C, Torres-Odio S, et al. Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice. Sci Adv. 2021 May 26;7(22):eabe7548. doi: 10.1126/sciadv.abe7548. PMID: 34039599.
Davenport BJ, Morrison TE, Kedl RM, Klarquist J. Conserved and Novel Mouse CD8 T Cell Epitopes within SARS-CoV-2 Spike Receptor Binding Domain Protein Identified following Subunit Vaccination. J Immunol. 2021 May 10:ji2100195. doi: 10.4049/jimmunol.2100195. PMID: 33972373.
Kim DI, Cho YB, Lim Y, Hong SH, Hahm B, Lee SM, Kang SC, Seo YJ. Chios mastic gum inhibits influenza A virus replication and viral pathogenicity. J Gen Virol. 2021 Jan 8. doi: 10.1099/jgv.0.001550. PMID: 33416468.
Kumar P, Arbieva ZH, Maienschein-Cline M, Ganesh BB, Ramasamy S, Prabhakar BS. Induction of Antigen-Independent Proliferation of Regulatory T-Cells by TNF Superfamily Ligands OX40L and GITRL. Methods Mol Biol. 2021;2248:63-71. doi: 10.1007/978-1-0716-1130-2_4. PMID: 33185867.
Mishra S, Liao W, Liu Y, Yang M, Ma C, Wu H, Zhao M, Zhang X, Qiu Y, Lu Q, Zhang N. TGF-β and Eomes control the homeostasis of CD8+ regulatory T cells. J Exp Med. 2021 Jan 4;218(1):e20200030. doi: 10.1084/jem.20200030. PMID: 32991667; PMCID: PMC7527976.
Yashiro T, Yura S, Tobita A, Toyoda Y, Kasakura K, Nishiyama C. Pterostilbene reduces colonic inflammation by suppressing dendritic cell activation and promoting regulatory T cell development. FASEB J. 2020 Sep 22. doi: 10.1096/fj.202001502R. PMID: 32964554.
Semionatto IF, Palameta S, Toscaro JM, Manrique-Rincón AJ, Ruas LP, Paes Leme AF, Bajgelman MC. Extracellular vesicles produced by immunomodulatory cells harboring OX40 ligand and 4-1BB ligand enhance antitumor immunity. Sci Rep. 2020 Sep 16;10(1):15160. doi: 10.1038/s41598-020-72122-3. PMID: 32939048.
Poudel B, Yorek MS, Mazgaeen L, Brown SA, Kanneganti TD, Gurung P. Acute IL-4 Governs Pathogenic T Cell Responses during Leishmania major Infection. Immunohorizons. 2020 Sep 18;4(9):546-560. doi: 10.4049/immunohorizons.2000076. PMID: 32948646.
Yagi Y, Kuwahara M, Suzuki J, Imai Y, Yamashita M. Glycolysis and subsequent mevalonate biosynthesis play an important role in Th2 cell differentiation. 2020 Aug 12. Biochem Biophys Res Commun. 2020;S0006-291X(20)31554-0. doi:10.1016/j.bbrc.2020.08.009.
Conor N. Gruber, Jorg J.A. Calis, Sofija Buta, et al. Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function. Immunity, 2020 Aug 3. https://doi.org/10.1016/j.immuni.2020.07.006
Long Y, Zhao X, Liu C, Xia C, Liu C. Activated inducible co-stimulator-positive (ICOS+ ) programmed death 1-positive (PD-1+ ) Tfh cells indicate disease activity and severity in ulcerative colitis patients [published online ahead of print, 2020 Jul 4]. Clin Exp Immunol. 2020;10.1111/cei.13485. doi:10.1111/cei.13485.
J. Michael Stolley, Timothy S. Johnston, Andrew G. Soerens, Lalit K. Beura, Pamela C. Rosato, Vineet Joag, Sathi P. Wijeyesinghe, Ryan A. Langlois, Kevin C. Osum, Jason S. Mitchell, David Masopust; Retrograde migration supplies resident memory T cells to lung-draining LN after influenza infection. J Exp Med3 June 2020; 217 (8): e20192197. doi: https://doi.org/10.1084/jem.20192197.
IL-6 Deficiency Exacerbates Allergic Asthma and Abrogates the Protective Effect of Allergic Inflammation against Streptococcus pneumoniae Pathogenesis. Taylor Schmit, Sumit Ghosh, Ram Kumar Mathur, Tyler Barnhardt, Ganesh Ambigapathy, Min Wu, Colin Combs, M. Nadeem Khan. The Journal of Immunology June 15, 2020, ji1900755; DOI: 10.4049/jimmunol.1900755.
» View on Journal of Immunology
Correlation of the levels of DNA-binding inhibitor Id3 and regulatory T cells with SLE disease severity. ChenLiu. SenYu. RongJin. YanLong. SongsongLu. YingSong. XiuyuanSun. Xiao-HongSun. YuZhang. J Autoimmun. 2020 Jun 11;102498. doi: 10.1016/j.jaut.2020.102498.
Franco da Cunha F, Andrade-Oliveira V, Candido de Almeida D, Borges da Silva T, Naffah de Souza Breda C, Costa Cruz M, Faquim-Mauro EL, Antonio Cenedeze M, Ioshie Hiyane M, Pacheco-Silva A, Aparecida Cavinato R, Torrecilhas AC, Olsen Saraiva Câmara N. Extracellular Vesicles isolated from Mesenchymal Stromal Cells Modulate CD4+ T Lymphocytes Toward a Regulatory Profile. Cells. 2020 Apr 23;9(4). pii: E1059. doi: 10.3390/cells9041059Extracellular Vesicles isolated from Mesenchymal Stromal Cells Modulate CD4+ T Lymphocytes Toward a Regulatory Profile. Cells. 2020 Apr 23;9(4). pii: E1059. doi: 10.3390/cells9041059
Woolsey C, Jankeel A, Matassov D, et al. Immune correlates of postexposure vaccine protection against Marburg virus. Sci Rep. 2020;10(1):3071. Published 2020 Feb 20. doi:10.1038/s41598-020-59976-3.
Adami AJ, Bracken SJ, Guernsey LA, et al. Early-life antibiotics attenuate regulatory T cell generation and increase the severity of murine house dust mite-induced asthma. Pediatr Res. 2018;84(3):426-434. doi:10.1038/s41390-018-0031-y.
Manrique-Rincón AJ, Beraldo CM, Toscaro JM and Bajgelman MC. 2017. Exploring Synergy in Combinations of Tumor-Derived Vaccines That Harbor 4-1BBL, OX40L, and GM-CSF. Front Immunol. doi: 10.3389/fimmu.2017.01150.
Li YY, Pearson JA, Chao C, Peng J, Zhang X, Zhou Z, Liu Y, Wong FS and Wen L. 2017. Nucleotide-binding oligomerization domain-containing protein 2 (Nod2) modulates T1DM susceptibility by gut microbiota. J Autoimmun. doi: 10.1016/j.jaut.2017.05.007.
Bowen JR, Quicke KM, Maddur MS, O'Neal JT, McDonald CE, Fedorova NB, Puri V, Shabman RS, Pulendran B and Suthar MS. 2017. Zika Virus Antagonizes Type I Interferon Responses during Infection of Human Dendritic Cells. PLoS Pathog. doi: 10.1371/journal.ppat.1006164
Yanagita T, Murata Y, Tanaka D2, Motegi SI, Arai E, Daniwijaya EW, Hazama D, Washio K, Saito Y, Kotani T, Ohnishi H, Oldenborg PA, Garcia NV, Miyasaka M, Ishikawa O, Kanai Y, Komori T and Matozaki T. 2017. Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy. JCI Insight. DOI: 10.1172/jci.insight.89140
Guthmiller JJ, Graham AC, Zander RA, Pope RL and Butler NS. 2017. Cutting Edge: IL-10 Is Essential for the Generation of Germinal Center B Cell Responses and Anti-Plasmodium Humoral Immunity. DOI:10.4049/jimmunol.1601762
Cruz LO, Hashemifar SS, Wu CJ, Cho S, Nguyen DT. Lin LL, Khan AA and Lu LF. 2017. Excessive expression of miR-27 impairs Treg-mediated immunological tolerance. J. Clin. Invest. doi:10.1172/JCI88415
Lambracht-Washington D and Rosenberg RN. 2014. A non-inflammatory immune response in aged DNA Aβ42 immunized mice supports its safety for possible use as immunotherapy in AD patients. doi:10.1016/j.neurobiolaging.2014.12.011
Karo JM, Schatz DG and Sun JC. 2014. The RAG Recombinase Dictates Functional Heterogeneity and Cellular Fitness in Natural Killer Cells. Cell. 159(1): 94-107.
Yasuoka T, Kuwahara M, Yamada T, Maruyama S, Suzuki J, Taniguchi M, Yasukawa M, and Yamashita M. 2016. The Transcriptional Repressor Gfi1 Plays a Criticol Role in the Development of NKT1- and NKT2- Type iNKT Cells. PLOS One. doi:10.1371/journal.pone.0157395
Kuwahara M, Ise W, Ochi M, Suzuki J, Kometani K, Saho M, Izumoto M, Matsumoto A, Takemori N, Takemori A, Shinoda K, Nakayama T, Ohara O, Yasukawa M, Sawasaki T, Kurosaki T and Yamashita M. 2016. Bach2–Batf Interactions Control Th2-type Immune Response by Regulating the IL-4 Amplification Loop. Nat. Commun. doi:10.1038/ncomms12596
Kalokhe AS, Ibegbu CC, Kaur SP, Amara RR, Kelley ME, Rio C and Stephenson R. 2016. Initimate Partner Violence is Associated with Increased CD4+ T-Cell Activation Among HIV-Negative High-Risk Women. Pathog. Immun. doi: 10.20411/pai.v1i1.120
Adam L. Burrack, Ellen J. Spartz, Jackson F. Raynor, Iris Wang, Margaret Olson, Ingunn M. Stromnes. Combination PD-1 and PD-L1 Blockade Promotes Durable Neoantigen-Specific T Cell-Mediated Immunity in Pancreatic Ductal Adenocarcinoma. Cell Rep. 2019 Aug 20;28(8):2140-2155.e6. doi: 10.1016/j.celrep.2019.07.059
» View on PubMed
Laura S. Angelo, Lynn H. Bimler, Rana Nikzad, Kevin Aviles-Padilla, and Silke Paust. CXCR6+ NK Cells in Human Fetal Liver and Spleen Possess Unique Phenotypic and Functional Capabilities. Front Immunol. 2019 Mar 19;10:469. doi: 10.3389/fimmu.2019.00469
» View on PubMed
Foxp3 / Transcription Factor Fix/Perm Concentrate (4X), TNB-1020
Xu K, Li MO. Delivery of membrane impermeable molecules to primary mouse T lymphocytes. STAR Protoc. 2021 Aug 17;2(3):100757. doi: 10.1016/j.xpro.2021.100757. PMID: 34458872; PMCID: PMC8377589.
Pingili AK, Chaib M, Sipe LM, et al. Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer. Cell Rep. 2021 Jun 22;35(12):109285. doi: 10.1016/j.celrep.2021.109285. PMID: 34161764.
Li X, Li Z, Hou D, Zhao Y, Wang C and Li X. 2016. The bovine endometrial epithelial cells promote the differentiation of trophoblast stem-like cells to binucleate trophoblast cells. Cytotechnology. DOI: 10.1007/s10616-016-9994-x
RBC Lysis Buffer
Young IC, Wu B, Andricovich J, Chuang ST, Li R, Tzatsos A, Wu RC, Wu MY. Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling. Cell Rep. 2021 Nov 23;37(8):110036. doi: 10.1016/j.celrep.2021.110036. PMID: 34818550.
Fan Z, Jan S, Hickey JC, Davies DH, Felgner J, Felgner PL, Guan Z. Multifunctional Dendronized Polypeptides for Controlled Adjuvanticity. Biomacromolecules. 2021 Nov 17. doi: 10.1021/acs.biomac.1c01052. Epub ahead of print. PMID: 34788023.
Li X, Liu J, Xing Z, Tang J, Sun H, Zhang X, Lv S, Chen Z, Shi M, Chen M, Zuo S, Lyu X, He Y. Polymorphonuclear myeloid-derived suppressor cells link inflammation and damage response after trauma. J Leukoc Biol. 2021 Oct 12. doi: 10.1002/JLB.3MA0821-029R. Epub ahead of print. PMID: 34636072.
Prosser A, Dart S, Larma-Cornwall I, Lucas M. Flow cytometric characterization of tissue-resident lymphocytes after murine liver and heart transplantation. STAR Protoc. 2021 Sep 15;2(4):100810. doi: 10.1016/j.xpro.2021.100810. PMID: 34568841; PMCID: PMC8449134.
Trott DW, Islam MT, Buckley DJ, Donato AJ, Dutson T, Sorensen ES, Cai J, Gogulamudi VR, Phuong TTT, Lesniewski LA. T lymphocyte depletion ameliorates age-related metabolic impairments in mice. Geroscience. 2021 Apr 24. doi: 10.1007/s11357-021-00368-4. PMID: 33893902.
Bake S, Pinson MR, Pandey S, et al. Prenatal Alcohol-Induced Sex Differences in Immune, Metabolic and Neurobehavioral Outcomes in Adult Rats. Brain Behav Immun. 2021 Aug 11:S0889-1591(21)00497-9. doi: 10.1016/j.bbi.2021.08.207. PMID: 34390803.
Mi L, Wang Y, Xu H, Wang Y, Wu J, Dai H, Zhang Y. PRAK Promotes the Pathogen Clearance by Macrophage Through Regulating Autophagy and Inflammasome Activation. Front Immunol. 2021 Apr 16;12:618561. doi: 10.3389/fimmu.2021.618561. PMID: 33936034; PMCID: PMC8085562.
Xia L, Shi Y, Su J, Friedemann T, et al. Shufeng Jiedu, a promising herbal therapy for moderate COVID-19:Antiviral and anti-inflammatory properties, pathways of bioactive compounds, and a clinical real-world pragmatic study. Phytomedicine. 2020 Oct 22:153390. doi: 10.1016/j.phymed.2020.153390. PMID: 33158717; PMCID: PMC7581328.
Jennifer S. Chen, Jessica D.S. Grassmann, Uthaman Gowthaman, Sam J. Olyha, Tregony Simoneau, M. Cecilia Berin, Stephanie C. Eisenbarth, Adam Williams. Flow cytometric identification of Tfh13 cells in mouse and human. Journal of Allergy and Clinical Immunology, 2020. https://doi.org/10.1016/j.jaci.2020.04.063.
Jackson LP, Tjoa BA, Mellert H, Pestano GA. Development of a TCR beta repertoire assay for profiling liquid biopsies from NSCLC donors. Cancer Drug Resist 2020;3. http://dx.doi.org/10.20517/cdr.2020.07.
Kim IS, Gao Y, Welte T, et al. Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms. Nat Cell Biol. 2019;21(9):1113-1126. doi:10.1038/s41556-019-0373-7.
Flow Staining Buffer (1X)
Burbach BJ, O'Flanagan SD, Shao Q, et al. Irreversible electroporation augments checkpoint immunotherapy in prostate cancer and promotes tumor antigen-specific tissue-resident memory CD8+ T cells. Nat Commun. 2021 Jun 23;12(1):3862. doi: 10.1038/s41467-021-24132-6. PMID: 34162858.
» View on NatureCommunications
Pingili AK, Chaib M, Sipe LM, et al. Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer. Cell Rep. 2021 Jun 22;35(12):109285. doi: 10.1016/j.celrep.2021.109285. PMID: 34161764.
Monensin Solution (1000X)
Dodagatta-Marri E, Ma HY, Liang B, et al. Integrin αvβ8 on T cells suppresses anti-tumor immunity in multiple models and is a promising target for tumor immunotherapy. Cell Rep. 2021 Jul 6;36(1):109309. doi: 10.1016/j.celrep.2021.109309. PMID: 34233193.
Foxp3 / Transcription Factor Fix/Perm Diluent (1X), TNB-1022
Xu K, Li MO. Delivery of membrane impermeable molecules to primary mouse T lymphocytes. STAR Protoc. 2021 Aug 17;2(3):100757. doi: 10.1016/j.xpro.2021.100757. PMID: 34458872; PMCID: PMC8377589.